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[慢性酒精中毒时迷走神经的病理变化]

[Pathological changes in the vagus nerves in chronic alcoholism].

作者信息

Guo Y P, Mc Leod J G

机构信息

PUMC Hospital, Chinese Academy of Medical Sciences, Beijing.

出版信息

Zhonghua Shen Jing Jing Shen Ke Za Zhi. 1990 Aug;23(4):234-6, 255.

PMID:2174764
Abstract

A systematic morphometric examination of the vagus nerves at different levels obtained at autopsy in 4 control subjects and 6 alcoholic patients. Morphometric studies on myelinated fibres were performed on the nerve at the mid-cervical, lung hilum and diaphragmatic levels. In the patients with alcoholic neuropathy there was a significant reduction in density of myelinated fibers in the distal part of the vagus nerves when compared with controls. The more severe distal degeneration in the nerves and the pathological changes of axonal degeneration distally are consistent with the dying back neuropathy. The relation between the secondary segmental demyelination and degeneration of the involved nerves were discussed.

摘要

对4名对照受试者和6名酒精性患者尸检时获取的不同水平迷走神经进行系统的形态计量学检查。对颈中部、肺门和膈肌水平的神经进行了有髓纤维的形态计量学研究。与对照组相比,酒精性神经病变患者迷走神经远端的有髓纤维密度显著降低。神经更严重的远端变性以及远端轴突变性的病理变化与逆行性神经病变一致。讨论了受累神经的继发性节段性脱髓鞘与变性之间的关系。

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[Pathological changes in the vagus nerves in chronic alcoholism].[慢性酒精中毒时迷走神经的病理变化]
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引用本文的文献

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Human alcohol-related neuropathology.人类酒精相关神经病理学。
Acta Neuropathol. 2014 Jan;127(1):71-90. doi: 10.1007/s00401-013-1233-3. Epub 2013 Dec 27.
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Degeneration of intrapancreatic nerve fibers after chronic alcohol administration in mice.小鼠长期酒精给药后胰腺内神经纤维的退变
Int J Pancreatol. 1997 Apr;21(2):165-71. doi: 10.1007/BF02822388.