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[糖尿病患者迷走神经的病理学研究]

[A pathologic study of the vagus nerves in diabetes mellitus].

作者信息

Gou Y P

出版信息

Zhonghua Shen Jing Jing Shen Ke Za Zhi. 1989 Feb;22(1):32-4, 62.

PMID:2805976
Abstract

A systematic morphometric examination at different levels of the vagus nerves obtained at autopsy in 4 control subjects and 3 diabetics was carried out. Morphometric studies on myelinated fibres were performed on the nerve at mid-cervical, lung hilum and diaphragmatic levels. In 2 insulin-dependent diabetics the density of myelinated fibres was below the lower limit of the control range at all levels. In all the diabetic subjects there was significant reduction in the density of fibres at the most distal level in the nerves. The teased fibre studies showed predominantly changes of axonal degeneration. They are consistent with the findings of abnormal vagal function in diabetics.

摘要

对4名对照受试者和3名糖尿病患者尸检时获取的不同水平迷走神经进行了系统的形态计量学检查。对颈中部、肺门和膈肌水平的神经进行了有髓纤维的形态计量学研究。在2名胰岛素依赖型糖尿病患者中,所有水平的有髓纤维密度均低于对照范围的下限。在所有糖尿病受试者中,神经最远端水平的纤维密度显著降低。 teased纤维研究显示主要为轴突变性变化。它们与糖尿病患者迷走神经功能异常的发现一致。 (注:原文中“teased fibre”不太明确具体准确意思,可能是“分离纤维”之类的,这里保留英文未翻译)

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