Chen Pei-Yen, Luo Chin-Hsiang, Chen Mei-Chin, Tsai Feng-Jie, Chang Nai-Fang, Shih Ying
Department of Cosmetic Science, Providence University 200 Chungchi Rd., Taichung 43301, Taiwan; E-Mails:
Int J Mol Sci. 2011;12(6):3810-20. doi: 10.3390/ijms12063810. Epub 2011 Jun 9.
Cobalt phthalocyanine (CoPc) films were deposited on the surface of a screen-printed carbon electrode using a simple drop coating method. The cyclic voltammogram of the resulting CoPc modified screen-printed electrode (CoPc/SPE) prepared under optimum conditions shows a well-behaved redox couple due to the (Co(I)/Co(II)) system. The CoPc/SPE surface demonstrates excellent electrochemical activity towards the oxidation of sulfur in a 0.01 mol·L(-1) NaOH. A linear calibration curve with the detection limit (D(L), S/N = 3) of 0.325 mg·L(-1) was achieved by CoPc/SPE coupled with flow injection analysis of the sulfur concentration ranging from 4 to 1120 mg·L(-1). The precision of the system response was evaluated (3.60% and 3.52% RSD for 12 repeated injections), in the range of 64 and 480 mg·L(-1) sulfur. The applicability of the method was successfully demonstrated in a real sample analysis of sulfur in anti-acne creams, and good recovery was obtained. The CoPc/SPE displayed several advantages in sulfur determination including easy fabrication, high stability, and low cost.
采用简单的滴涂法将钴酞菁（CoPc）薄膜沉积在丝网印刷碳电极表面。在最佳条件下制备的所得CoPc修饰丝网印刷电极（CoPc/SPE）的循环伏安图显示，由于（Co（I）/Co（II））体系，呈现出良好的氧化还原对。CoPc/SPE表面在0.01 mol·L⁻¹ NaOH中对硫的氧化表现出优异的电化学活性。通过CoPc/SPE与流动注射分析相结合，对4至1120 mg·L⁻¹范围内的硫浓度进行分析，得到了检测限（D(L)，S/N = 3）为0.325 mg·L⁻¹的线性校准曲线。在64至480 mg·L⁻¹硫的范围内评估了系统响应的精密度（12次重复进样的相对标准偏差分别为3.60%和3.52%）。该方法的适用性在抗痤疮霜中硫的实际样品分析中得到成功验证，并获得了良好的回收率。CoPc/SPE在硫测定中显示出几个优点，包括易于制备、高稳定性和低成本。
