von Rosen A, Frisell J, Azavedo E, Auer G
Department of Surgery, Södersjukhuset, Stockholm, Sweden.
Eur J Surg Oncol. 1990 Dec;16(6):471-4.
Non-palpable breast cancers detected by mammography in women participating in the ongoing screening project at Södersjukhuset, Stockholm, Sweden, were classified by morphological and cytochemical malignancy grading. The women's age ranged between 40 and 64 years, and the clinical course was followed for a minimum of 5 years after primary treatment. No significant difference in disease-free survival was observed in the 66 cases studied (mean age 58 years) where 28% of the tumors were aneuploid and 72% euploid. Our results indicate that prognosis, even for patients with potentially highly malignant tumors, can be altered when their tumors are detected and treated at an early stage.
在瑞典斯德哥尔摩南医院正在进行的筛查项目中，通过乳房X线摄影检测出的不可触及的乳腺癌，按照形态学和细胞化学恶性分级进行分类。这些女性年龄在40至64岁之间，在初次治疗后至少随访了5年。在研究的66例病例（平均年龄58岁）中，未观察到无病生存率的显著差异，其中28%的肿瘤为非整倍体，72%为整倍体。我们的结果表明，即使对于患有潜在高恶性肿瘤的患者，如果在早期阶段检测到并治疗其肿瘤，预后也可能会改变。
