老年人的谵妄
Delirium in older adults.
作者信息
Popeo Dennis M
机构信息
Mount Sinai School of Medicine, New York, NY, USA.
出版信息
Mt Sinai J Med. 2011 Jul-Aug;78(4):571-82. doi: 10.1002/msj.20267.
Abstract
Delirium is a common neuropsychiatric syndrome in the elderly that can occur in several different settings caused by several different processes. It is common and causes increased morbidity and mortality to those affected. This clinical review discusses the prediction, prevention, diagnosis, and treatment of delirium in the elderly population. Several strategies to predict delirium are noted with the discussion of pharmacological and nonpharmacological trials of prevention and treatment. Diagnosis of delirium, specifically with the use of objective instruments, is discussed, as is the evidence for pharmacological and nonpharmacological treatment strategies. Discussion of the neurobiology and genetic markers for delirium may elucidate further areas for future research.
摘要
谵妄是老年人常见的神经精神综合征，可在由多种不同过程引起的多种不同情况下发生。它很常见，会增加受影响者的发病率和死亡率。这篇临床综述讨论了老年人群中谵妄的预测、预防、诊断和治疗。文中指出了几种预测谵妄的策略，并讨论了预防和治疗的药理学和非药理学试验。文中讨论了谵妄的诊断，特别是使用客观工具的诊断，以及药理学和非药理学治疗策略的证据。对谵妄的神经生物学和遗传标记的讨论可能会阐明未来研究的更多领域。
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