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[关于免疫球蛋白使用的实用评论]

[Practical comments on the use of immunoglobulins].

作者信息

Lewandowicz-Uszyńska Aleksandra, Swierkot Jerzy

机构信息

III Katedra i Klinika Pediatrii, Immunologii i Reumatologii Wieku Rozwojowego, Akademia Medyczna we Wrocławiu.

出版信息

Pol Merkur Lekarski. 2011 Jun;30(180):448-51.

Abstract

The paper contains basic information relating to treatment with immunoglobulin. Presented indications for their use, among others: primary immunodeficiency, Kawasaki disease, Guillain-Barre syndrome, chronic lymphocytic leukemia, primary thrombocytopenia. The factors to consider when choosing a preparation: the content of IgG, IgA, method of administration (intravenous or subcutaneous). The most frequent side effects, depending on the organ localization. Presented at risk (obesity, diabetes, renal failure, hypovolemia) in which these symptoms may occur especially frequently, which should be taken into account in the conduct of therapy (adequate hydration, low-dose, slow infusion).

摘要

该论文包含了与免疫球蛋白治疗相关的基本信息。列举了其使用指征,包括:原发性免疫缺陷、川崎病、格林-巴利综合征、慢性淋巴细胞白血病、原发性血小板减少症。选择制剂时需考虑的因素:IgG、IgA含量,给药方式(静脉注射或皮下注射)。根据器官定位列出了最常见的副作用。还介绍了这些症状可能特别频繁出现的高危情况(肥胖、糖尿病、肾衰竭、血容量不足),在治疗过程中应予以考虑(充分补液、低剂量、缓慢输注)。

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