通过线粒体 DNA 单倍群分析揭示中世纪古代西西伯利亚人的遗传特征。

Genetic features of ancient West Siberian people of the Middle Ages, revealed by mitochondrial DNA haplogroup analysis.

机构信息

Department of Natural History Sciences, Graduate School of Science, Hokkaido University, Kita-ku, Sapporo, Japan.

出版信息

J Hum Genet. 2011 Aug;56(8):602-8. doi: 10.1038/jhg.2011.68. Epub 2011 Jul 14.

DOI:10.1038/jhg.2011.68

Abstract

In order to investigate the genetic features of ancient West Siberian people of the Middle Ages, we studied ancient DNA from bone remains excavated from two archeological sites in West Siberia: Saigatinsky 6 (eighth to eleventh centuries) and Zeleny Yar (thirteenth century). Polymerase chain reaction amplification and nucleotide sequencing of mitochondrial DNA (mtDNA) succeeded for 9 of 67 specimens examined, and the sequences were assigned to mtDNA haplogroups B4, C4, G2, H and U. This distribution pattern of mtDNA haplogroups in medieval West Siberian people was similar to those previously reported in modern populations living in West Siberia, such as the Mansi, Ket and Nganasan. Exact tests of population differentiation showed no significant differences between the medieval people and modern populations in West Siberia. The findings suggest that some medieval West Siberian people analyzed in the present study are included in direct ancestral lineages of modern populations native to West Siberia.

摘要

为了研究中世纪西伯利亚西部古代人群的遗传特征，我们对西伯利亚西部两个考古遗址出土的骨骼遗骸中的古代 DNA 进行了研究：Saigatinsky 6 （8 至 11 世纪）和 Zeleny Yar （13 世纪）。对 67 个样本中的 9 个进行了聚合酶链反应扩增和核苷酸测序，并且将这些序列分配给了线粒体 DNA（mtDNA）单倍群 B4、C4、G2、H 和 U。中世纪西伯利亚西部人群的这种 mtDNA 单倍群分布模式与先前在西伯利亚西部生活的现代人群（如曼西人、凯特人和涅涅茨人）的分布模式相似。种群分化的精确检验显示，中世纪人群与西伯利亚西部的现代人群之间没有显著差异。这些发现表明，本研究分析的一些中世纪西伯利亚西部人群属于西伯利亚西部本地现代人群的直系祖先。