• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

4-羟基-6-(4-甲氧基苯基)-4-苯基-1,3-二氮杂环己烷-2-硫酮

4-Hy-droxy-6-(4-meth-oxy-phen-yl)-4-phenyl-1,3-diazinane-2-thione.

作者信息

Devarajegowda H C, Roopashree K R, Mohammed Irfan Ali, Sankolli Ravish

出版信息

Acta Crystallogr Sect E Struct Rep Online. 2011 Apr 1;67(Pt 4):o815. doi: 10.1107/S1600536811008002. Epub 2011 Mar 9.

DOI:10.1107/S1600536811008002
PMID:21754101
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3099814/
Abstract

In the title compound, C(17)H(18)N(2)O(2)S, the 1,3-diazinane-2-thione ring system is not coplanar with the benzene ring and meth-oxy-phenyl ring system, the dihedral angle between the planes being 65.58 (13) and 89.18 (10)°, respectively. The crystal structure is characterized by inter-molecular O-H⋯S, N-H⋯S, N-H⋯O and C-H⋯S hydrogen bonding.

摘要

在标题化合物C(17)H(18)N(2)O(2)S中，1,3 - 二氮杂环己烷 - 2 - 硫酮环系与苯环和甲氧基苯基环系不共面，平面间的二面角分别为65.58 (13)°和89.18 (10)°。晶体结构的特征在于分子间存在O - H⋯S、N - H⋯S、N - H⋯O和C - H⋯S氢键。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fc45/3099814/fd6e6f0d10c0/e-67-0o815-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fc45/3099814/9c7b15fc63dc/e-67-0o815-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fc45/3099814/fd6e6f0d10c0/e-67-0o815-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fc45/3099814/9c7b15fc63dc/e-67-0o815-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fc45/3099814/fd6e6f0d10c0/e-67-0o815-fig2.jpg

相似文献

1
4-Hy-droxy-6-(4-meth-oxy-phen-yl)-4-phenyl-1,3-diazinane-2-thione.4-羟基-6-(4-甲氧基苯基)-4-苯基-1,3-二氮杂环己烷-2-硫酮
Acta Crystallogr Sect E Struct Rep Online. 2011 Apr 1;67(Pt 4):o815. doi: 10.1107/S1600536811008002. Epub 2011 Mar 9.
2
Ethyl 4-hy-droxy-6-(4-hy-droxy-phen-yl)-4-trifluoro-methyl-2-sulfanyl-idene-1,3-diazinane-5-carboxyl-ate ethanol monosolvate.4-羟基-6-(4-羟基苯基)-4-三氟甲基-2-硫亚基-1,3-二嗪烷-5-羧酸乙酯乙醇单溶剂合物
Acta Crystallogr Sect E Struct Rep Online. 2011 May 1;67(Pt 5):o1280-1. doi: 10.1107/S1600536811015376. Epub 2011 Apr 29.
3
(E)-Methyl 2-({2-eth-oxy-6-[(E)-(hy-droxy-imino)-meth-yl]phen-oxy}meth-yl)-3-phenyl-acrylate.（E）-2-（{2-乙氧基-6-[(E)-(羟基亚氨基)甲基]苯氧基}甲基）-3-苯基丙烯酸甲酯
Acta Crystallogr Sect E Struct Rep Online. 2012 May 1;68(Pt 5):o1373. doi: 10.1107/S1600536812014596. Epub 2012 Apr 13.
4
Crystal structure of ethyl 6-(2-fluoro-phen-yl)-4-hy-droxy-2-sulfanyl-idene-4-tri-fluoro-meth-yl-1,3-diazinane-5-carboxyl-ate.6-(2-氟苯基)-4-羟基-2-硫亚基-4-三氟甲基-1,3-二嗪烷-5-羧酸乙酯的晶体结构
Acta Crystallogr E Crystallogr Commun. 2015 Apr 2;71(Pt 5):o268-9. doi: 10.1107/S2056989015005836. eCollection 2015 May 1.
5
(E)-4-Bromo-N'-(4-hy-droxy-3-meth-oxy-benzyl-idene)benzohydrazide monohydrate.（E）-4-溴-N'-（4-羟基-3-甲氧基苄叉基）苯甲酰肼一水合物
Acta Crystallogr Sect E Struct Rep Online. 2012 Apr 1;68(Pt 4):o1069-70. doi: 10.1107/S160053681201032X. Epub 2012 Mar 14.
6
1-(2-Hy-droxy-eth-yl)-3-(3-meth-oxy-phen-yl)thio-urea.1-（2-羟基乙基）-3-（3-甲氧基苯基）硫脲
Acta Crystallogr Sect E Struct Rep Online. 2010 Sep 4;66(Pt 10):o2487-8. doi: 10.1107/S1600536810034665.
7
1-(3-Hy-droxy-phen-yl)-3-(3-meth-oxy-phenyl)thio-urea.1-（3-羟基苯基）-3-（3-甲氧基苯基）硫脲
Acta Crystallogr Sect E Struct Rep Online. 2012 Feb 1;68(Pt 2):o530. doi: 10.1107/S1600536812002553. Epub 2012 Jan 31.
8
3-[Hy-droxy(3-meth-oxy-phen-yl)methyl-idene]-2-(2-oxo-2-phenyl-eth-yl)-3,4-dihydro-2H-1λ(6),2-benzothia-zine-1,1,4-trione.3-[羟基(3-甲氧基苯基)亚甲基]-2-(2-氧代-2-苯基乙基)-3,4-二氢-2H-1λ(6),2-苯并噻嗪-1,1,4-三酮
Acta Crystallogr Sect E Struct Rep Online. 2012 Apr 1;68(Pt 4):o978-9. doi: 10.1107/S1600536812009002. Epub 2012 Mar 7.
9
2-[2-(3-Chloro-phen-yl)-2-oxoeth-yl]-4-hy-droxy-3-(3-meth-oxy-benzo-yl)-2H-1λ(6),2-benzothia-zine-1,1-dione.2-[2-(3-氯苯基)-2-氧代乙基]-4-羟基-3-(3-甲氧基苯甲酰基)-2H-1λ(6),2-苯并噻嗪-1,1-二酮
Acta Crystallogr Sect E Struct Rep Online. 2012 Apr 1;68(Pt 4):o980-1. doi: 10.1107/S1600536812009014. Epub 2012 Mar 7.
10
Crystal structure of (2E)-1-(4-hy-droxy-3-meth-oxy-phen-yl)-3-(4-hy-droxy-phen-yl)prop-2-en-1-one.（2E）-1-（4-羟基-3-甲氧基苯基）-3-（4-羟基苯基）丙-2-烯-1-酮的晶体结构
Acta Crystallogr Sect E Struct Rep Online. 2014 Oct 15;70(Pt 11):o1158-9. doi: 10.1107/S1600536814021953. eCollection 2014 Nov 1.

本文引用的文献

1
A short history of SHELX.SHELX简史。
Acta Crystallogr A. 2008 Jan;64(Pt 1):112-22. doi: 10.1107/S0108767307043930. Epub 2007 Dec 21.
2
Effect of substituted pyrimidines on growth and biosynthesis of microorganisms.取代嘧啶对微生物生长和生物合成的影响。
Cancer Res. 1959 Apr;19(3 Part 2):15-30.
3
The effect of 5-fluorouracil and 5-fluorocytosine on the development of the filarial nematodes Brugia pahangi and Dirofilaria immitis.
Acta Trop. 1981 Sep;38(3):289-304.
4
Synthesis and biological activity of some 5-substituted 2,4-diamino-6-alkylpyrimidines. 3.一些5-取代的2,4-二氨基-6-烷基嘧啶的合成与生物活性。3.
J Med Chem. 1972 Jun;15(6):662-5. doi: 10.1021/jm00276a025.
5
[Antibacterial activity of pyrimidine and pyrrolo-(3,2-d)-pyrimidine derivatives].[嘧啶和吡咯并-(3,2-d)-嘧啶衍生物的抗菌活性]
Farmakol Toksikol. 1972 Jul;35(4):466-71.
6
Some pyrimidines of biological and medicinal interest. I.一些具有生物学和医学意义的嘧啶。I.
Prog Med Chem. 1969;6:67-134. doi: 10.1016/s0079-6468(08)70197-8.
7
Chemotherapeutic agents, XVIII: Synthesis of pi-deficient pyrimidines and fused pyrimidines as leishmanicidal agents.化疗药物，第十八篇：作为杀利什曼原虫剂的缺π嘧啶和稠合嘧啶的合成
Arch Pharm (Weinheim). 1990 Nov;323(11):895-9. doi: 10.1002/ardp.19903231103.