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(2R,6S)-叔丁基 2-(二苯甲基氨基甲酰基)-6-甲基吗啉-4-羧酸酯

(2R,6S)-tert-Butyl 2-(benzhydryl-carbamo-yl)-6-methyl-morpholine-4-carboxyl-ate.

作者信息

Wang Haiyang, Xia Guangxin, Liu Xuejun, Shen Jingkang

出版信息

Acta Crystallogr Sect E Struct Rep Online. 2011 Jun 1;67(Pt 6):o1437. doi: 10.1107/S1600536811017764. Epub 2011 May 20.

DOI:10.1107/S1600536811017764
PMID:21754815
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3120296/
Abstract

The title compound, C(24)H(30)N(2)O(4), was obtained by the reaction of (2R,6S)-4-(tert-but-oxy-carbon-yl)-6-methyl-morpho-line-2-carb-oxy-lic acid with diphenyl-methanamine in dimethyl-formamide solution. The morpholine ring is in a chair conformation. In the crystal, weak inter-molecular C-H⋯O hydrogen bonds link mol-ecules into chains along the b axis.

摘要

标题化合物C(24)H(30)N(2)O(4)是通过(2R,6S)-4-(叔丁氧羰基)-6-甲基吗啉-2-羧酸与二苯甲胺在二甲基甲酰胺溶液中反应得到的。吗啉环呈椅式构象。在晶体中，弱的分子间C-H⋯O氢键将分子沿b轴连接成链。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/130a/3120296/ef6d44c43d70/e-67-o1437-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/130a/3120296/641c8442852d/e-67-o1437-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/130a/3120296/ef6d44c43d70/e-67-o1437-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/130a/3120296/641c8442852d/e-67-o1437-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/130a/3120296/ef6d44c43d70/e-67-o1437-fig2.jpg

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