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(3R,4S,5R)-3,5-双-[(叔丁基-二甲基-硅烷基)-氧基]-4-甲氧基-环己-1-烯-羧酸甲酯

(3R,4S,5R)-Methyl 3,5-bis-[(tert-butyl-dimethyl-sil-yl)-oxy]-4-meth-oxy-cyclo-hex-1-ene-carboxyl-ate.

作者信息

Liu Ri, Shi Yu, Xu Chun-Xiu, Li Yi-Liang

机构信息

School of Chinese Materia Medica, Tianjin University of Traditional Chinese Medicine, Tianjin 300193, People's Republic of China.

出版信息

Acta Crystallogr Sect E Struct Rep Online. 2013 Apr 5;69(Pt 5):o632. doi: 10.1107/S1600536813007551. Print 2013 May 1.

DOI:10.1107/S1600536813007551
PMID:23723799
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3647833/
Abstract

The title compound, C21H42O5Si2, was synthesized from (3R,4S,5R)-methyl 3,5-bis-[(tert-butyl-dimethyl-sil-yl)-oxy]-4-hy-droxy-cyclo-hex-1-ene-carboxyl-ate by an esterification reaction. The cyclo-hexene ring adopts a half-chair conformation. In the crystal, mol-ecules are linked via C-H⋯O hydrogen bonds, forming helical chains propagating along [010].

摘要

标题化合物C21H42O5Si2是由(3R,4S,5R)-3,5-双-[(叔丁基二甲基硅基)氧基]-4-羟基环己-1-烯羧酸甲酯通过酯化反应合成的。环己烯环呈半椅式构象。在晶体中，分子通过C—H⋯O氢键相连，形成沿[010]方向延伸的螺旋链。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a201/3647833/510d9a6bf157/e-69-0o632-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a201/3647833/510d9a6bf157/e-69-0o632-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a201/3647833/510d9a6bf157/e-69-0o632-fig1.jpg

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