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症状性脊髓海绵状血管畸形:显微手术治疗的适应证和结果。

Symptomatic spinal cavernous malformations: indication for microsurgical treatment and outcome.

机构信息

Department of Neurosurgery, Klinik für Neurochirurgie, Universitätsklinikum Schleswig-Holstein, Campus Kiel, Arnold-Heller-Straße 3, 24105 Kiel, Germany.

出版信息

Eur Spine J. 2011 Oct;20(10):1765-70. doi: 10.1007/s00586-011-1898-z. Epub 2011 Jul 14.

Abstract

PURPOSE

We demonstrate clinical features, therapy and outcome of 14 patients with symptomatic spinal cavernous malformations (CM).

METHODS

We retrospectively reviewed all patients who underwent microsurgical treatment of symptomatic spinal CM during the last decade in our department through an analysis of our database.

RESULTS

We analyzed the data of 14 patients (11 females, 3 males) with symptomatic spinal CM in a range of 16-77 years (mean age 47.8 years). Seven patients (50%) experienced significant improvement of their symptoms rapidly after surgery. The remaining seven patients presented new non pre-existing complaints, which improved gradually with a favourable outcome at the last follow-up examination in six cases.

CONCLUSION

Microsurgical treatment under perioperative electrophysiological monitoring is justified to prevent severe neurofunctional deterioration in symptomatic spinal CM. Although some of the patients deteriorate after surgery, the symptoms are rapidly declining with a favourable outcome in majority of them.

摘要

目的

我们展示了 14 例有症状的脊髓海绵状血管畸形(CM)患者的临床特征、治疗方法和结果。

方法

我们通过分析数据库,回顾性研究了过去十年中在我科接受显微手术治疗有症状脊髓 CM 的所有患者。

结果

我们分析了 14 例有症状脊髓 CM 患者(11 名女性,3 名男性)的数据,年龄 16-77 岁(平均年龄 47.8 岁)。7 例(50%)患者术后迅速出现症状显著改善。其余 7 例患者出现新的非预先存在的症状,其中 6 例在最后一次随访检查时,症状逐渐改善,预后良好。

结论

在围手术期电生理监测下进行显微手术治疗是合理的,可以预防有症状脊髓 CM 患者的严重神经功能恶化。尽管有些患者术后病情恶化,但大多数患者的症状迅速减轻,预后良好。

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