Faculty of Medicine, Université de Sherbrooke, Sherbrooke, Quebec; Researcher, Research Centre, Charles LeMoyne Hospital, Greenfield Park, Quebec.
Can J Psychiatry. 2011 Jun;56(6):348-57. doi: 10.1177/070674371105600606.
To document the use of psychotropic drugs in Quebec older adult population with a depressive or anxiety disorder.
Data from the Enquête sur la Santé des Aînés (ESA) study conducted between 2005 and 2008 using a representative sample (n = 1869) of community-dwelling adults aged 65 years and older were used to examine the use of psychotropic drugs in the Quebec older adult population.
Our results indicate that only 46.9% of the older adults with a diagnosis of depression or anxiety during the 24-month period studied according to the Régie de l'assurance maladie du Quebec (RAMQ) register used antidepressants (AD) for 400 days (12.9 months) on average during this period. Also, 59% of the RAMQ's mental health disorder patients used a mean daily dose of 5 mg of a diazepam equivalent for 338 days (10.9 months) on average during the same period. However, 10.0% of the older adults without any symptoms (ESA) at T1 and at T2 and any RAMQ depression and anxiety diagnosis between T0 and T2 were AD users during the 24-month period studied. They represent 26.2% of the AD users and consumed them for 494 days (15.9 months) on average during the 24-month period studied. Finally, the number of days of AD and benzodiazepine use was not associated with partial or total remission.
This result questions the population effectiveness of these drugs in this population.
记录魁北克老年人群中患有抑郁或焦虑障碍的精神药物使用情况。
使用 2005 年至 2008 年间进行的 Enquête sur la Santé des Aînés（ESA）研究的数据，该研究采用了具有代表性的样本（n=1869），包括 65 岁及以上的社区居住成年人，用于检查魁北克老年人群中精神药物的使用情况。
我们的研究结果表明，在根据魁北克医疗保险局（RAMQ）登记册研究的 24 个月期间，仅有 46.9%的被诊断患有抑郁或焦虑的老年人使用抗抑郁药（AD），平均使用时间为 400 天（12.9 个月）。此外，在同一时期，59%的 RAMQ 精神健康障碍患者平均每天使用 5 毫克地西泮当量，使用时间为 338 天（10.9 个月）。然而，在 T1 和 T2 时没有任何症状（ESA）且在 T0 至 T2 期间没有任何 RAMQ 抑郁和焦虑诊断的 10.0%的老年人在 24 个月的研究期间是 AD 使用者。他们占 AD 使用者的 26.2%，在 24 个月的研究期间平均使用 AD 药物 494 天（15.9 个月）。最后，AD 和苯二氮䓬类药物的使用天数与部分或完全缓解无关。
这一结果对这些药物在该人群中的人群疗效提出了质疑。
