Massamba Victoire, Vasiliadis Helen-Maria, Préville Michel
Clinical Sciences Program, Faculty of Medicine and Health Sciences, Université de Sherbrooke, Sherbrooke, QC, Canada.
Department of Community Health, University of Sherbrooke, Sherbrooke, QC, Canada.
BMC Res Notes. 2017 Aug 22;10(1):419. doi: 10.1186/s13104-017-2714-6.
To determine the proportion of older adults receiving guideline concordant antidepressant therapy and to determine patient, prescriber and organizational factors associated with adequate antidepressant therapy.
The study included secondary analyses of data collected in the Étude sur la Santé des Aînés (ESA) Services study on older adults recruited while consulting in primary care clinics in one of the largest health regions of the province of Québec. Antidepressant users (n = 349) were identified from information collected from the Régie de l'Assurance Maladie du Québec (RAMQ) pharmaceutical database which holds information on all drugs dispensed to all residents covered under the public drug plan. Adequacy of antidepressant treatment was measured using three criteria: adequacy of daily dose; length of prescription (≥455 days); and ≥3 visits to the antidepressant-prescribing physician in the first 3 months after initiation of therapy. Multivariate logistic regression analyses were used to study antidepressant treatment adequacy as a function of individual, provider and healthcare system factors.
Among the antidepressant users, 44% received an adequate antidepressant treatment filling all three criteria. None of the factors studied were associated with the probability of receiving adequate treatment filling all three criteria. Psychological distress was associated with having an adequate number of visits in the 3 months following initiation. Males and those living in a metropolitan and urban area were less likely to receive an adequate dose.
Future research should consider factors associated with perceived effectiveness and patient treatment preferences that may explain receipt of adequate antidepressant treatment in older adults.
确定接受符合指南的抗抑郁治疗的老年人比例,并确定与充分抗抑郁治疗相关的患者、开处方者和组织因素。
该研究包括对在魁北克省最大的健康区域之一的初级保健诊所就诊时招募的老年人进行的“老年人健康研究”(ESA)服务研究中收集的数据进行二次分析。从魁北克医疗保险局(RAMQ)的药品数据库收集的信息中识别出抗抑郁药使用者(n = 349),该数据库保存了所有公共药品计划覆盖居民所配发的所有药物的信息。使用三个标准衡量抗抑郁治疗的充分性:每日剂量是否充足;处方时长(≥455天);以及治疗开始后的前3个月内≥3次就诊于抗抑郁药开处方医生。多变量逻辑回归分析用于研究抗抑郁治疗充分性作为个体、提供者和医疗保健系统因素的函数。
在抗抑郁药使用者中,44%接受了符合所有三个标准的充分抗抑郁治疗。所研究的因素均与符合所有三个标准接受充分治疗的可能性无关。心理困扰与治疗开始后3个月内有足够的就诊次数相关。男性以及居住在大都市和城市地区的人接受充足剂量的可能性较小。
未来的研究应考虑与感知疗效和患者治疗偏好相关的因素,这些因素可能解释老年人接受充分抗抑郁治疗的情况。