Lunn Katharine F
Department of Clinical Sciences, Colorado State University, 300 West Drake Road, Fort Collins, CO 80523-1620, USA.
Vet Clin North Am Small Anim Pract. 2011 Jul;41(4):727-44, vi. doi: 10.1016/j.cvsm.2011.03.020. Epub 2011 May 23.
Critically ill animals may have preexisting renal disease or develop acute kidney injury as a consequence of their presenting complaint. Age, concurrent medical therapy, electrolyte and fluid imbalances, and exposure to potential nephrotoxicants are factors that predispose to acute kidney injury. Many risk factors are correctable or manageable, and these should be addressed whenever possible. Measurement of serum creatinine is insensitive for the detection of acute kidney injury, and clinicians should consider assessment of other parameters such as urine output, urinalysis, and urine chemistry results. A stepwise approach for management of acute kidney injury in small animal patients is outlined.
危重病动物可能先前就患有肾脏疾病，或者因其就诊的主诉而发生急性肾损伤。年龄、同时进行的药物治疗、电解质和液体失衡以及接触潜在的肾毒性物质都是易引发急性肾损伤的因素。许多风险因素是可以纠正或控制的，应尽可能加以处理。血清肌酐的测定对急性肾损伤的检测不敏感，临床医生应考虑评估其他参数，如尿量、尿液分析和尿液化学检查结果。本文概述了小动物患者急性肾损伤的逐步管理方法。
