Rivers B J, Walter P A, Polzin D J, King V L
Department of Small Animal Clinical Sciences, College of Veterinary Medicine, University of Minnesota, St. Paul, USA.
J Vet Intern Med. 1997 Jul-Aug;11(4):250-60. doi: 10.1111/j.1939-1676.1997.tb00099.x.
In human beings, intrarenal blood flow impedance, expressed as the resistive index (RI) and obtained by duplex Doppler ultrasonography, has been used to aid in diagnosis and prognosis of renal failure. Higher than normal values for RI were obtained in 3 of 4 dogs with acute tubular necrosis (ATN) and in 5 of 10 dogs with glomerulonephrosis (GN). Normalization of RI was observed in 2 dogs with ATN evaluated serially during treatment. Increased RI values were obtained in 9 of 10 cats with nonobstructive renal disease and in 2 of 5 cats with obstructive renal disease. Normalization of RI was observed in 3 cats with renal failure in which treatment was effective (1 with obstruction; 2 with nonobstructive disease). The magnitude of increase in RI did not correlate with the magnitude of concurrent renal dysfunction. These results suggest that duplex Doppler evaluation of intrarenal RI is more useful as an ancillary diagnostic technique in azotemic dogs with ATN than in those with GN and in azotemic dogs with nonobstructive than in those with obstructive disease.
在人类中,肾内血流阻抗以阻力指数(RI)表示,通过双功多普勒超声检查获得,已被用于辅助肾衰竭的诊断和预后评估。4只患有急性肾小管坏死(ATN)的犬中有3只以及10只患有肾小球肾炎(GN)的犬中有5只的RI值高于正常。在治疗期间连续评估的2只患有ATN的犬中观察到RI恢复正常。10只患有非梗阻性肾病的猫中有9只以及5只患有梗阻性肾病的猫中有2只的RI值升高。在3只肾衰竭且治疗有效的猫中观察到RI恢复正常(1只患有梗阻性肾病;2只患有非梗阻性疾病)。RI升高的幅度与同时存在的肾功能障碍的程度无关。这些结果表明,双功多普勒评估肾内RI作为辅助诊断技术,在患有ATN的氮质血症犬中比在患有GN的犬中更有用,在患有非梗阻性疾病的氮质血症犬中比在患有梗阻性疾病的犬中更有用。