McCord Kelly W, Webb Craig B
Small Animal Internal Medicine, Department of Clinical Sciences, James L. Voss Veterinary Teaching Hospital, Colorado State University, 300 West Drake Road, Fort Collins, CO 80523, USA.
Vet Clin North Am Small Anim Pract. 2011 Jul;41(4):745-58, vi. doi: 10.1016/j.cvsm.2011.04.002. Epub 2011 May 23.
This article reviews the common pathophysiology that constitutes hepatic dysfunction, regardless of the inciting cause. The systemic consequences of liver failure and the impact of this condition on other organ systems are highlighted. The diagnostic tests available for determining the cause and extent of liver dysfunction are outlined, treatment strategies aimed at supporting hepatic health and recovery are discussed, and prognosis is briefly covered. The article emphasizes the fact that because of the central role of the liver in maintaining normal systemic homeostasis, hepatic dysfunction cannot be effectively addressed as an isolated entity.
本文综述了构成肝功能障碍的常见病理生理学,无论其诱发原因如何。强调了肝衰竭的全身后果以及这种情况对其他器官系统的影响。概述了可用于确定肝功能障碍原因和程度的诊断测试,讨论了旨在支持肝脏健康和恢复的治疗策略,并简要介绍了预后情况。本文强调,由于肝脏在维持正常全身内环境稳定中起着核心作用,因此不能将肝功能障碍作为一个孤立的实体来有效处理。