Liu Wei, Du Juan-Juan, Li Zeng-Hui, Zhang Xin-Yu, Zuo Hou-Dong
Sichuan Key Laboratory of Medical Imaging, Department of Radiology, The Affiliated Hospital of North Sichuan Medical College, Nanchong 637000, Sichuan Province, China.
World J Clin Cases. 2021 Dec 6;9(34):10418-10429. doi: 10.12998/wjcc.v9.i34.10418.
Acute pancreatitis (AP) is a very common acute disease, and the mortality rate of severe AP (SAP) is between 15% and 35%. The main causes of death are multiple organ dysfunction syndrome and infections. The mortality rate of patients with SAP related to liver failure is as high as 83%, and approximately 5% of the SAP patients have fulminant liver failure. Liver function is closely related to the progression and prognosis of AP. In this review, we aim to elaborate on the clinical manifestations and mechanism of liver injury in patients with AP.
急性胰腺炎（AP）是一种非常常见的急性疾病，重症急性胰腺炎（SAP）的死亡率在15%至35%之间。主要死亡原因是多器官功能障碍综合征和感染。与肝衰竭相关的SAP患者死亡率高达83%，约5%的SAP患者发生暴发性肝衰竭。肝功能与AP的进展及预后密切相关。在本综述中，我们旨在阐述AP患者肝损伤的临床表现及机制。
