蒙特利尔认知评估：大型脑卒中试验中的简短认知评估。
The montreal cognitive assessment: short cognitive evaluation in a large stroke trial.
机构信息
National Stroke Research Institute, Florey Neuroscience Institutes, Melbourne, Australia.
出版信息
Stroke. 2011 Sep;42(9):2642-4. doi: 10.1161/STROKEAHA.111.619486. Epub 2011 Jul 14.
BACKGROUND AND PURPOSE
Cognitive function is often ignored in stroke research trials. The brief Montreal Cognitive Assessment (MoCA) may be sensitive to stroke-related cognitive deficits.
METHODS
We evaluated the feasibility of administering the MoCA at 3 months in a large stroke trial (A Very Early Rehabilitation Trial [AVERT]).
RESULTS
Data (blinded to intervention group) are presented for 294 patients with mean age of 70.6 years (SD, 12.8); 220 (75%) completed the MoCA, 54 (18%) had missing data, and 20 (7%) had died. Of those surviving to 3 months, the MoCA was completed by 87% with mild stroke, 79% with moderate stroke, and 67% with severe stroke on admission. Mean MoCA score was 21.1 (SD 7.5) out of 30; only 78 of 220 (35%) patients attained the "normal" cutoff (≥26).
CONCLUSIONS
The MoCA is a feasible global cognitive screening tool in stroke trials. Clinical Trial Registration- URL: www.anzctr.org.au/trial_view.aspx?ID=1266. Unique identifier: ACTRN12606000185561.
背景与目的
认知功能在中风研究试验中经常被忽视。简短蒙特利尔认知评估（MoCA）可能对与中风相关的认知缺陷敏感。
方法
我们评估了在一项大型中风试验（早期康复试验[AVERT]）中在 3 个月时进行 MoCA 测试的可行性。
结果
数据（对干预组进行盲法评估）呈现给 294 名平均年龄为 70.6 岁（标准差，12.8）的患者；220 名（75%）完成了 MoCA，54 名（18%）数据缺失，20 名（7%）死亡。在存活至 3 个月的患者中，轻度中风患者中有 87%完成了 MoCA，中度中风患者中有 79%，重度中风患者中有 67%。MoCA 平均得分为 30 分中的 21.1（标准差 7.5）；220 名患者中只有 78 名（35%）达到“正常”截止值（≥26）。
结论
MoCA 是中风试验中一种可行的全面认知筛查工具。临床试验注册- URL：www.anzctr.org.au/trial_view.aspx？ID=1266. 独特标识符：ACTRN12606000185561.
Zotero 插件