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传染病爆发的准中性理论。

Quasi-neutral theory of epidemic outbreaks.

机构信息

Departamento de Física, Instituto de Física Aplicada, Universidad Nacional de San Luis-CONICET, San Luis, Argentina.

出版信息

PLoS One. 2011;6(7):e21946. doi: 10.1371/journal.pone.0021946. Epub 2011 Jul 8.

DOI:10.1371/journal.pone.0021946
PMID:21760930
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3132777/
Abstract

Some epidemics have been empirically observed to exhibit outbreaks of all possible sizes, i.e., to be scale-free or scale-invariant. Different explanations for this finding have been put forward; among them there is a model for "accidental pathogens" which leads to power-law distributed outbreaks without apparent need of parameter fine tuning. This model has been claimed to be related to self-organized criticality, and its critical properties have been conjectured to be related to directed percolation. Instead, we show that this is a (quasi) neutral model, analogous to those used in Population Genetics and Ecology, with the same critical behavior as the voter-model, i.e. the theory of accidental pathogens is a (quasi)-neutral theory. This analogy allows us to explain all the system phenomenology, including generic scale invariance and the associated scaling exponents, in a parsimonious and simple way.

摘要

有些流行病被经验观察到表现出所有可能规模的爆发,即无标度或标度不变。对于这一发现提出了不同的解释;其中有一种“偶然病原体”模型,它导致幂律分布的爆发,而不需要明显的参数微调。有人声称这个模型与自组织临界性有关,其临界性质被推测与定向渗流有关。相反,我们表明这是一个(准)中性模型,类似于在人口遗传学和生态学中使用的模型,具有与投票模型相同的临界行为,即偶然病原体理论是一个(准)中性理论。这种类比使我们能够以简洁和简单的方式解释所有的系统现象,包括通用的标度不变性和相关的标度指数。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/53b9/3132777/86ce37070d50/pone.0021946.g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/53b9/3132777/3049b4e2a933/pone.0021946.g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/53b9/3132777/22573a686c05/pone.0021946.g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/53b9/3132777/d12a68e17ea6/pone.0021946.g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/53b9/3132777/b2ebb414c8c9/pone.0021946.g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/53b9/3132777/1386e79ca31c/pone.0021946.g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/53b9/3132777/86ce37070d50/pone.0021946.g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/53b9/3132777/3049b4e2a933/pone.0021946.g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/53b9/3132777/22573a686c05/pone.0021946.g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/53b9/3132777/d12a68e17ea6/pone.0021946.g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/53b9/3132777/b2ebb414c8c9/pone.0021946.g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/53b9/3132777/1386e79ca31c/pone.0021946.g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/53b9/3132777/86ce37070d50/pone.0021946.g006.jpg

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