Centro de Investigaciones Toxicológicas, Juan B. Alberdi 2986, Ciudad de Buenos Aires, Argentina.
Clin Toxicol (Phila). 2011 Jul;49(6):508-9. doi: 10.3109/15563650.2011.594800. Epub 2011 Jul 15.
For the first time in Argentina, we describe an outbreak of contact dermatitis. New pairs of shoes caused intense pruritus, pain, and eruption, followed by edema, blisters, and a severe negative impact on the epidermal barrier of the feet. We identify dimethylfumarate as the causal agent and suggest an analytical method for its fast identification.
这是阿根廷首次描述一起接触性皮炎爆发事件。新鞋会引起强烈瘙痒、疼痛和皮疹,随后出现水肿、水疱,并对脚部的表皮屏障造成严重负面影响。我们确定富马酸二甲酯是致病原因,并提出了一种快速鉴定它的分析方法。