Demirbaş Duygu, Aksoy Elif, Polat Senol, Serin Gediz, Unal Omer Faruk, Tanyeri Hasan
Acıbadem Etiler Tıp Merkezi, Kulak Burun Boğaz Hastalıkları Bölümü, İstanbul, Türkiye.
Kulak Burun Bogaz Ihtis Derg. 2011 Jul-Aug;21(4):198-203. doi: 10.5606/kbbihtisas.2011.026.
In this study, we assessed the effect of endonasal phototherapy on quality of life, nasal obstruction and the other symptoms in allergic rhinitis with visual analog scale (VAS), sinonasal outcome test-20 (SNOT-20), and acoustic rhinometry.
Twenty-four patients (6 males, 18 females; mean age 41.3±13.0 years; range 20 to 60 years) suffering allergic rhinitis refractory to anti allergic drugs for at least two years were enrolled in the study. Each patient underwent a total of six sessions of endonasal phototherapy with Rhinolight (Rhinolight Ltd, Szeged, Hungary) performed three times a week for two weeks. During course of the investigation, additional therapy was not applied to any of the patients. Before and one month after treatment, patients completed visual analog scale and SNOT-20 forms and nasal obstruction was evaluated with acoustic rhinometry.
After the treatment, the mean VAS score and the mean total SNOT-20 score were found lower than the results before the therapy (p=0.0001, p=0.0001). A significant decrease was found in the scores of sneezing, nasal discharge, postnasal drainage, coughing after treatment (p=0.0001). During objective evaluation of nasal obstruction with acoustic rhinometry, no statistically significant difference was found between pre- and post-treatment findings.
Endonasal phototherapy is an effective modality in the treatment of symptomatology in allergic rhinitis patients refractory to antiallergic drugs. It is detected that endonasal phototherapy has positive effects on the quality of life. However, no effect on nasal obstruction was found with acoustic rhinometry which is an objective method.
在本研究中，我们使用视觉模拟量表（VAS）、鼻窦结局测试-20（SNOT-20）和声反射鼻测量法评估鼻内光疗对变应性鼻炎患者生活质量、鼻阻塞及其他症状的影响。
本研究纳入了24例（6例男性，18例女性；平均年龄41.3±13.0岁；范围20至60岁）对抗过敏药物治疗至少两年无效的变应性鼻炎患者。每位患者总共接受6次使用Rhinolight（匈牙利塞格德Rhinolight有限公司）进行的鼻内光疗，每周进行3次，共两周。在研究过程中，未对任何患者应用额外治疗。治疗前和治疗后1个月，患者完成视觉模拟量表和SNOT-20表格，并使用声反射鼻测量法评估鼻阻塞情况。
治疗后，平均VAS评分和平均SNOT-20总分均低于治疗前结果（p = 0.0001，p = 0.0001）。治疗后打喷嚏、流涕、鼻后滴漏、咳嗽的评分显著降低（p = 0.0001）。在用声反射鼻测量法对鼻阻塞进行客观评估时，治疗前后结果之间未发现统计学显著差异。
鼻内光疗是治疗对抗过敏药物难治的变应性鼻炎患者症状的一种有效方式。已检测到鼻内光疗对生活质量有积极影响。然而，作为一种客观方法的声反射鼻测量法未发现其对鼻阻塞有影响。
