Department of Toxicology, "Akademik Danilo Soldatovic", Belgrade University-Faculty of Pharmacy, Vojvode Stepe 450, 11221 Belgrade, Serbia.
Food Chem Toxicol. 2011 Oct;49(10):2586-93. doi: 10.1016/j.fct.2011.06.078. Epub 2011 Jul 7.
The aim of this work was to assess the risk due to mercury (Hg), dichlorodiphenyltrichloroethane (DDT) and non-dioxin-like polychlorinated biphenyls (ndl PCBs) intake via fish consumption in Serbia. We have developed 24 scenarios using four concentration levels (mean, maximum, 50th and 95th percentile) of contaminants, determined in 521 samples of fish products available on Serbian market; two consumption levels (Food and Agriculture Organization/World Health Organization data and recommendation of American Heart Association); and three body weights (5th, 50th and 95th percentile). All the values concerning the intake of DDT are below the corresponding health based guidance value. Calculated weekly intake of Hg using maximal concentration, intake of 340g/week and 5th percentile of body weight exceeded the provisional tolerable weekly intake (PTWI). When maximal and 95th percentile concentration of ndl PCBs was used, weekly intakes exceeded a "guidance value" with one exception i.e., when 95th percentile of concentration along with 95th percentile of body weight were used. Concerning Hg and ndl PCBs, when extreme concentrations were used, HIs exceeded the value of 1, indicating that fish and fishery products may pose a threat to consumer's health.
本研究旨在评估塞尔维亚人因食用鱼类而摄入汞（Hg）、滴滴涕（DDT）和非二恶英类多氯联苯（ndl PCBs）的风险。我们使用了四种污染物浓度水平（平均值、最大值、第 50 百分位数和第 95 百分位数），共涉及 521 个在塞尔维亚市场上可获得的鱼类产品样本；两种消费水平（粮农组织/世界卫生组织数据和美国心脏协会的建议）；以及三种体重（第 5、第 50 和第 95 百分位数）来开发了 24 种情景。所有与 DDT 摄入量有关的值均低于相应的基于健康的指导值。使用最大浓度、每周摄入 340 克和第 5 百分位数的体重计算出的每周 Hg 摄入量超过了暂定每周耐受摄入量（PTWI）。当使用 ndl PCBs 的最大和第 95 百分位数浓度时，每周摄入量超过了“指导值”，只有一个例外，即当使用第 95 百分位数浓度和第 95 百分位数体重时。关于 Hg 和 ndl PCBs，当使用极端浓度时，HI 值超过了 1，这表明鱼类和渔业产品可能对消费者的健康构成威胁。
