Department of Psychology, University of Tabriz, Tabriz, Iran.
Int J Psychophysiol. 2011 Sep;81(3):230-6. doi: 10.1016/j.ijpsycho.2011.06.016. Epub 2011 Jul 19.
To establish whether dynamic EEG changes in children with attention-deficit/hyperactivity disorder (ADHD) differ from those observed in controls, the authors investigated the effect of the continuous performance test (CPT) on delta, theta, alpha and beta frequency bands. High-resolution electroencephalography (EEG) was recorded during eyes-open resting and CPT performance in 16 right-handed children meeting the DSM-IV criteria for ADHD and 16 age-matched controls. Significant CPT vs. eyes-open differences in EEG activities was observed in children with ADHD. In particular, switching to CPT induced an alpha power increase in children with ADHD and an alpha power decrease in controls. This may reflect a primary deficit associated with cortical hypoarousal in ADHD. These EEG results agree with behavioral findings leading the authors to suggest that dynamic changes in neural network activities are impaired in children with ADHD.
为了确定注意缺陷多动障碍（ADHD）儿童的动态脑电图变化是否与对照组观察到的不同，作者研究了连续性能测试（CPT）对 delta、theta、alpha 和 beta 频段的影响。在 16 名符合 DSM-IV ADHD 标准的右利手儿童和 16 名年龄匹配的对照组中，在睁眼静息和 CPT 表现期间记录高分辨率脑电图（EEG）。在 ADHD 儿童中观察到 EEG 活动的 CPT 与睁眼差异具有统计学意义。特别是，CPT 转换诱导 ADHD 儿童的 alpha 功率增加，而对照组的 alpha 功率降低。这可能反映了 ADHD 中与皮质低唤醒相关的主要缺陷。这些脑电图结果与行为学发现一致，导致作者提出 ADHD 儿童的神经网络活动动态变化受损。
