Department of Oral and Maxillofacial Surgery, Central Hospital, Västerås, Sweden.
Int J Oral Maxillofac Surg. 2011 Dec;40(12):1441-4. doi: 10.1016/j.ijom.2011.06.016. Epub 2011 Jul 20.
A case of osteomyelitis in a 71-year-old woman with paroxysmal nocturnal hemoglobinuria (PNH) is reported. Osteomyelitis of the jaw is a well known condition of the oral and maxillofacial region that may cause severe morbidity. It is well documented that vaso-occlusive crises in sickle cell anaemia, a hemolytic blood disorder, can make the jaw bone susceptible to osteomyelitis. The authors report a case proposing an association between PNH and osteomyelitis of the mandible.
报告了一例 71 岁女性阵发性睡眠性血红蛋白尿症（PNH）合并骨髓炎的病例。颌骨骨髓炎是口腔颌面部一种众所周知的疾病，可导致严重的发病率。已有充分的文献记载，镰状细胞性贫血是一种溶血性血液疾病，其中血管阻塞危象可使颌骨易患骨髓炎。作者报告了一例病例，提出 PNH 与下颌骨骨髓炎之间存在关联。
