BioDetection Systems, Amsterdam, The Netherlands.
Reprod Toxicol. 2011 May;31(4):558–61. doi: 10.1016/j.reprotox.2011.02.012.
In spite of extensive research in the area over many decades, there is still a shortage of accepted alternative testing methods in reproductive toxicology. Of the variety of alternative methods developed for reproductive toxicity testing not a single one has reached regulatory acceptance. Although various standardized tests have been described, their predictability and applicability domains have so far not satisfactorily been defined. In the near future this situation will only change if new approaches are explored. Current regulatory needs in combination with technological innovations set the scene for rapid progress in this area.
尽管在过去几十年中，该领域进行了广泛的研究，但生殖毒理学中仍然缺乏被广泛认可的替代测试方法。在为生殖毒性测试开发的各种替代方法中，没有一种方法达到监管部门的认可。尽管已经描述了各种标准化测试，但迄今为止，它们的可预测性和适用性范围尚未得到令人满意的定义。在不久的将来，只有探索新方法，这种情况才会改变。当前的监管需求结合技术创新为该领域的快速发展创造了条件。
