Department of Psychiatry, Namsos Hospital, Namsos, Norway.
Int Psychogeriatr. 2012 Jan;24(1):151-8. doi: 10.1017/S1041610211001141. Epub 2011 Jul 18.
Depression is a common disorder in late life. As the elderly population continues to grow worldwide, depression is also likely to become an increasing health problem. The aim of this study was to examine changes in prevalence of depression in various age cohorts over an 11-year period.
This study involved two cross-sectional studies (HUNT 2 and HUNT 3) of all adult inhabitants of the Norwegian county of Nord-Trøndelag with an 11 year-interval between the two studies. The participants aged 45 years or above at HUNT 2 and with a valid depression rating at both HUNT 2 (baseline) and HUNT 3 (follow-up) (N = 16517), were included and divided into five-year age cohorts. Depression was measured by the depression subscale of the Hospital Anxiety and Depression Scale (HADS-D).
A significant increase in depression was found in all age cohorts from 76 years at follow-up, with the greatest increase (9.6%) in the oldest age cohort (86-90 years at follow-up). The incidence of depression is increasing with age, with over 10% new cases in all age cohorts aged 81 years and above at follow-up. About 5% of the participants in all age cohorts reported depression at both measure points, and there is a decrease in recovery from depression from baseline to follow-up with increasing age.
We found increased prevalence of depression and a large number of new cases of depression in the oldest age cohorts.
抑郁症是老年人中常见的疾病。随着全球老年人口的不断增加，抑郁症也可能成为一个日益严重的健康问题。本研究旨在探讨在 11 年的时间内，不同年龄组的抑郁症患病率的变化。
本研究包括两次横断面研究（HUNT2 和 HUNT3），涉及挪威特隆赫姆郡的所有成年居民，两次研究之间间隔 11 年。在 HUNT2 时年龄在 45 岁及以上，且在 HUNT2（基线）和 HUNT3（随访）时均有有效抑郁评分的参与者（N=16517）被纳入并分为 5 岁年龄组。抑郁症通过医院焦虑和抑郁量表（HADS-D）的抑郁分量表来衡量。
所有年龄组在随访时的抑郁症都显著增加，年龄最大的组（86-90 岁）增加最多（9.6%）。随着年龄的增长，抑郁症的发病率也在增加，所有年龄组中，81 岁及以上的新发病例超过 10%。所有年龄组中有 5%左右的参与者在两个测量点都报告有抑郁症状，而且随着年龄的增长，从基线到随访，抑郁症的恢复情况有所下降。
我们发现年龄最大的年龄组中抑郁症的患病率增加，新发病例也较多。
