Department of Oral Pathology, Faculdade de Odontologia de Nova Friburgo, Universidade Federal Fluminense-Pólo Universitário de Nova Friburgo, Brazil.
J Craniomaxillofac Surg. 2012 Apr;40(3):e71-4. doi: 10.1016/j.jcms.2011.04.015. Epub 2011 Jul 20.
Head and neck chondrosarcomas are rare and potentially lethal tumours, which are even more uncommon in the head and neck region. The diagnosis of chondrosarcoma is based on the histopathological pattern of malignant chondroid tissue proliferation. The grade of malignancy and the histological surgical margins are some of the most important prognostic factors for this group of tumour. In the present report we described two cases of chondrosarcoma affecting the maxilla, which presented different behaviours. The first patient, with a high-grade tumour, died of local recurrence and the second patient, with a low-grade tumour, is alive and free of disease 60 months after the treatment. These two cases emphasize the importance of histological tumour grade and appropriate treatment for the prognosis.
头部和颈部软骨肉瘤是罕见的、潜在致命的肿瘤，在头颈部更为罕见。软骨肉瘤的诊断基于恶性软骨样组织增生的组织病理学模式。恶性程度分级和组织学手术切缘是该肿瘤群预后的最重要因素之一。在本报告中，我们描述了 2 例发生于上颌骨的软骨肉瘤，它们表现出不同的行为。第一例患者的肿瘤为高级别，死于局部复发，第二例患者的肿瘤为低级别，在治疗后 60 个月时仍存活且无疾病。这两个病例强调了组织学肿瘤分级和适当治疗对预后的重要性。
