Department of Clinical Nursing Science, Samsung Medical Center, Sungkyunkwan University School of Medicine, 50 Ilwon-Dong, Gangnam-Gu, Seoul 135-710, Republic of Korea.
Eur J Oncol Nurs. 2012 Apr;16(2):131-6. doi: 10.1016/j.ejon.2011.05.004. Epub 2011 Jul 20.
The aim of the study was to identify health-related quality of life (QOL) in persons diagnosed with cancer and to determine differences between the QOL over a 3-year period.
We investigated the QOL in cancer patients at baseline and 3 years later using the EORTC QLQ-C30 (European Organization for Research and Treatment of Cancer Quality of Life Questionnaire-Core 30) and the ECOG (Eastern Cooperative Oncology Group) Performance Status. Initially 216 participants (85 women, 131 men) were enrolled, and at the 3-year follow-up there were 126 (52 women, 74 men).
Scores on the function and symptom scales changed significantly between the baseline and the 3-year follow-up. Physical, role, and social functions improved, whereas problems with constipation worsened. The global QOL of the participants at the 3-year follow-up was lower than that of baseline, but it was not statistically significant. The QOL in cancer patients improved from the baseline to the 3-year follow-up.
The results could serve as a guideline for nurses interpreting the perspective of QOL in their own groups of patients, and improve the understanding of the significance of mean QOL scores and develop nursing interventions in the future.
本研究旨在确定癌症患者的健康相关生活质量（QOL），并确定 3 年内 QOL 的差异。
我们使用 EORTC QLQ-C30（欧洲癌症研究与治疗组织生活质量问卷-核心 30 项）和 ECOG（东部合作肿瘤学组）表现状态，在基线和 3 年后调查癌症患者的 QOL。最初纳入 216 名参与者（85 名女性，131 名男性），3 年后随访时有 126 名（52 名女性，74 名男性）。
基线和 3 年随访之间，功能和症状量表的评分显著变化。身体、角色和社会功能得到改善，而便秘问题恶化。3 年随访时参与者的总体 QOL低于基线，但无统计学意义。癌症患者的 QOL从基线到 3 年随访有所改善。
这些结果可以作为护士在解释自己患者群体的 QOL 观点时的指南，并提高对平均 QOL 得分意义的理解，并为未来制定护理干预措施。
