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美国新高血压指南的意义。

Implications of new hypertension guidelines in the United States.

机构信息

Department of Community Health, Warren Alpert Medical School of Brown University, 121 S Main St, Box G-S121, Providence, RI 02912, USA.

出版信息

Hypertension. 2011 Sep;58(3):361-6. doi: 10.1161/HYPERTENSIONAHA.111.175463. Epub 2011 Jul 18.

DOI:10.1161/HYPERTENSIONAHA.111.175463
PMID:21768528
Abstract

The American Heart Association Task Force released a scientific statement in 2007 for the treatment of hypertension in the prevention of coronary artery disease (CAD). These guidelines recommend more aggressive control of blood pressure (BP) among those at high risk for CAD: individuals with diabetes mellitus, chronic kidney disease, cardiovascular disease, congestive heart failure, or a 10-year Framingham risk score ≥10%. These individuals are advised to maintain a BP <130/80 mm Hg. We estimated the burden of uncontrolled BP among those at an increased risk of CAD using the updated task force guidelines. We used a cross-sectional analysis of National Health and Nutrition Examination Survey 2005-2008 participants. Participants were 24 989 adults aged 18 to 85 years. Using the old definition of hypertension (>140/90 mm Hg), 98 million (21%) Americans have hypertension. Using the updated guidelines, an additional 52 million (11%) American adults now have elevated BP requiring treatment, for a total of 150 million adults (32%). Adults with diabetes mellitus have the greatest population burden of uncontrolled BP (50.6 million), followed by adults with chronic kidney disease (43.7 million) and cardiovascular disease (43.3 million). Although individuals at a higher risk for CAD are more likely to be aware of their hypertension and to be taking antihypertension medication, they are less likely to have their BP under control. Additional efforts are needed in the treatment of elevated BP, especially among individuals with an increased risk of CAD.

摘要

美国心脏协会工作组于 2007 年发布了一份科学声明,内容涉及高血压的治疗以及冠心病(CAD)的预防。这些指南建议对具有 CAD 高危因素的人群(包括糖尿病患者、慢性肾脏病患者、心血管疾病患者、充血性心力衰竭患者或Framingham 风险评分 10 年≥10%的患者)采取更积极的血压控制措施。这些人应将血压控制在<130/80mmHg 以下。我们根据最新的工作组指南,估算了 CAD 风险增加人群中血压控制不佳的负担。我们对 2005-2008 年国家健康和营养调查的参与者进行了横断面分析。参与者为 24989 名年龄在 18 至 85 岁的成年人。根据高血压的旧定义(>140/90mmHg),有 9800 万人(21%)患有高血压。使用最新指南,现在又有 5200 万(11%)美国成年人血压升高需要治疗,总计有 1.5 亿成年人(32%)。患有糖尿病的成年人中血压控制不佳的人数最多(5060 万),其次是患有慢性肾脏病的成年人(4370 万)和心血管疾病患者(4330 万)。尽管 CAD 高危人群更有可能意识到自己患有高血压并服用抗高血压药物,但他们的血压控制率却较低。需要在治疗高血压方面做出更多努力,尤其是在 CAD 风险增加的人群中。

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