From the Department of Behavioral Science, Center on Drug and Alcohol Research, University of Kentucky College of Medicine, Lexington, KY.
J Addict Med. 2010 Sep;4(3):137-9. doi: 10.1097/ADM.0b013e3181c4bfd3.
: The purpose of this study was to examine both medical and nonmedical use of benzodiazepines among a community-based cohort of prescription opioid users.
: A total of 221 prescription opioid users from 2 rural Appalachian counties were recruited to participate in an interviewer-administered survey assessing sociodemographic characteristics, medical (source was valid prescription) and nonmedical (source other than prescription, such as dealer, friend, or family member) prescription drug use, illicit substance use, psychiatric disorders, and pain.
: Almost all of the participants (92.8%) reported lifetime benzodiazepine use and two thirds were current users. Only 29.3% of the current users had a legitimate prescription for a benzodiazepine. Current users were significantly more likely than nonusers to report nonmedical use of a variety of prescription opioids and other illicit drugs. The major source of benzodiazepines was a dealer.
: A high rate of nonmedical benzodiazepine use was observed in this sample of prescription opioid users. Physicians should, therefore, be aware of the potential for nonmedical use of benzodiazepines. Implications for treatment and future research are discussed.
本研究旨在调查基于社区的阿片类处方药物使用者队列中,苯二氮䓬类药物的医疗和非医疗用途。
从 2 个阿巴拉契亚农村县招募了 221 名阿片类处方药物使用者,参与一项访谈式调查,评估社会人口统计学特征、医疗(来源为有效处方)和非医疗(来源为非处方,如经销商、朋友或家庭成员)处方药物使用、非法物质使用、精神疾病和疼痛。
几乎所有参与者(92.8%)报告有过苯二氮䓬类药物的使用史,其中三分之二为当前使用者。仅有 29.3%的当前使用者有合法的苯二氮䓬类药物处方。当前使用者与非使用者相比,更有可能报告各种处方类阿片药物和其他非法药物的非医疗使用。苯二氮䓬类药物的主要来源是经销商。
在该组阿片类处方药物使用者中,观察到苯二氮䓬类药物的非医疗使用率很高。因此,医生应该意识到苯二氮䓬类药物存在非医疗使用的可能性。讨论了治疗和未来研究的意义。