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作为一种氧化还原发光开关的生物相容性羟基磷灰石纳米粒子。

Biocompatible hydroxyapatite nanoparticles as a redox luminescence switch.

机构信息

Key Laboratory of Nonferrous Metals Chemistry and Resources Utilization of Gansu Province and State Key Laboratory of Applied Organic Chemistry, College of Chemistry and Chemical Engineering, Lanzhou University, People's Republic of China.

出版信息

J Biol Inorg Chem. 2011 Dec;16(8):1135-40. doi: 10.1007/s00775-011-0815-6. Epub 2011 Jul 19.

DOI:10.1007/s00775-011-0815-6
PMID:21769606
Abstract

A redox luminescence switch was prepared by doping hydroxyapatite nanoparticles with CePO(4):Tb. The resulting multifunctional material exhibits good biocompatibility, biological affinity, and potential drug-carrying capability. The luminescent hydroxyapatite nanoparticles may find important applications in biomedical diagnostics, drug delivery, and biological sensors.

摘要

通过将羟基磷灰石纳米粒子掺杂铈磷酸(CePO(4):Tb)制备了一种氧化还原发光开关。所得多功能材料具有良好的生物相容性、生物亲和力和潜在的载药能力。发光羟基磷灰石纳米粒子在生物医学诊断、药物输送和生物传感器方面可能具有重要的应用。

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本文引用的文献

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Controlled synthesis of LaPO(4) and CePO(4) nanorods/nanowires.LaPO₄和CePO₄纳米棒/纳米线的可控合成。
Nanotechnology. 2005 Feb;16(2):282-6. doi: 10.1088/0957-4484/16/2/018. Epub 2005 Jan 14.
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Role of carboxylate chelating agents on the chemical, structural and textural properties of hydroxyapatite.羧酸类螫合剂对羟基磷灰石的化学、结构和织构性质的影响。
Dalton Trans. 2010 Nov 28;39(44):10644-51. doi: 10.1039/c0dt00251h. Epub 2010 Sep 30.
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Effects of modification of calcium hydroxyapatites by trivalent metal ions on the protein adsorption behavior.
羟基磷灰石纳米粒子辅助递送针对SATB1的短发夹RNA对人胶质瘤U251细胞体外和体内生长的抑制作用
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Internalization of hydroxyapatite nanoparticles in liver cancer cells.羟基磷灰石纳米颗粒在肝癌细胞中的内化
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Redox luminescence switch based on energy transfer in CePO4:Tb3+ nanowires.基于CePO4:Tb3+纳米线中能量转移的氧化还原发光开关。
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Increase in cell adhesiveness on a poly(ethylene terephthalate) fabric by sintered hydroxyapatite nanocrystal coating in the development of an artificial blood vessel.在人造血管研发中,通过烧结羟基磷灰石纳米晶体涂层提高聚对苯二甲酸乙二酯织物上的细胞粘附性。
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