Palanivelu R, Mary Saral A, Ruban Kumar A
School of Advanced Sciences, VIT University, Vellore 632014, Tamil Nadu, India.
School of Advanced Sciences, VIT University, Vellore 632014, Tamil Nadu, India.
Spectrochim Acta A Mol Biomol Spectrosc. 2014 Oct 15;131:37-41. doi: 10.1016/j.saa.2014.04.014. Epub 2014 Apr 18.
Hydroxyapatite (HAP) has sovereign biomedical application due to its excellent biocompatibility, chemical and crystallographic similitude with natural human bone. In this present work, we discussed about the role of pH in the synthesis of calcium phosphate compound using calcium nitrate tetrahydrate and di-ammonium hydrogen phosphate as starting materials by chemical precipitation method assisted with ultrasonic irradiation technique. 5% polyethylene glycol (PEG600) is added along with the precursors under various pH condition of 7, 9 and 11 respectively. The functional group analysis, crystallized size and fraction of crystallized size are confirmed using Fourier Transformation Infra-Red spectroscopy and X-ray diffraction pattern. Morphological observations are done by scanning electron microscope. The results revealed the presence of nanocrystalline hydroxyapatite at pH above 9.
羟基磷灰石（HAP）因其优异的生物相容性以及与天然人骨的化学和晶体学相似性而具有重要的生物医学应用。在本工作中，我们讨论了pH在以四水合硝酸钙和磷酸氢二铵为原料，通过超声辐照辅助化学沉淀法合成磷酸钙化合物中的作用。分别在pH为7、9和11的各种条件下，将5%的聚乙二醇（PEG600）与前驱体一起添加。使用傅里叶变换红外光谱和X射线衍射图谱确认官能团分析、结晶尺寸和结晶尺寸分数。通过扫描电子显微镜进行形态观察。结果表明在pH高于9时存在纳米晶羟基磷灰石。
