Telling Glenn C
Sanders Brown Center on Aging, University of Kentucky Medical Center, Lexington, KY 40506, USA.
Top Curr Chem. 2011;305:79-99. doi: 10.1007/128_2011_166.
Here we review the known strain profiles of various prion diseases of animals and humans, and how transgenic mouse models are being used to elucidate basic molecular mechanisms of prion propagation and strain variation and for assessing the zoonotic potential of various animal prion strains.
在此，我们回顾了动物和人类各种朊病毒疾病的已知毒株概况，以及转基因小鼠模型如何被用于阐明朊病毒传播和毒株变异的基本分子机制，以及评估各种动物朊病毒毒株的人畜共患病潜力。
