The New York Eye and Ear Infirmary, New York City, New York 10003, USA.
Ocul Immunol Inflamm. 2011 Aug;19(4):237-9. doi: 10.3109/09273948.2011.563898.
To report an immunocompetent patient with Nocardia exalbida endogenous endophthalmitis.
Case report.
Clinical-pathologic correlation and microbiologic evaluation were performed on an enucleated eye.
A 56-year-old man presented with rapidly progressive vision loss associated with a posterior choroidal mass and serous retinal detachment. Pathologic evaluation of the enucleated eye demonstrated endogenous endophthalmitis. Nocardia exalbida was identified microbiologically. Systemic workup failed to demonstrate definite foci of systemic infection or evidence of immunocompromise. Review of literature failed to identify previously reported cases of Nocardia exalbida endophthalmitis.
Nocardia can rarely cause isolated endogenous endophthalmitis in immunocompetent patients, which can contribute to a delay in diagnosis and vision loss. Endogenous Nocardia endophthalmitis typically occurs in immunocompromised patients with disseminated nocardiosis. Isolated endogenous Nocardia endophthalmitis in immunocompetent patients is rare. We describe isolated endogenous intraocular infection caused by Nocardia exalbida, a novel species, not previously associated with endophthalmitis.
报告 1 例免疫功能正常的 Nocardia exalbida 内源性眼内炎患者。
病例报告。
对一只眼球进行临床病理相关性和微生物学评估。
一名 56 岁男性因后葡萄膜肿块伴浆液性视网膜脱离而出现视力迅速下降。对眼球进行的病理评估显示为内源性眼内炎。微生物学鉴定出 Nocardia exalbida。全身检查未能发现明确的全身感染灶或免疫功能低下的证据。文献复习未发现先前报道的 Nocardia exalbida 眼内炎病例。
诺卡菌很少引起免疫功能正常患者孤立性内源性眼内炎，这可能导致诊断延迟和视力丧失。内源性诺卡菌眼内炎通常发生在患有播散性诺卡菌病的免疫功能低下患者中。免疫功能正常患者孤立性内源性眼内炎罕见。我们描述了由 Nocardia exalbida 引起的、以前与眼内炎无关的新型、孤立性内源性眼内感染。
