Royal Marsden Hospital, London, UK.
Anaesthesia. 2011 Oct;66(10):942-4. doi: 10.1111/j.1365-2044.2011.06815.x. Epub 2011 Jul 19.
We describe the case of a 25-year-old woman presented for elective lumbar decompression and microdiscectomy who, towards the end of her surgery, developed clinical signs of anaphylaxis. Skin testing later confirmed sensitisation to levobupivacaine and possibly MediShield, an anti-adhesion gel used following microdiscectomy. This case is the first confirmed case report of anaphylaxis in response to levobupivacaine. It also highlights the possibility that multiple agents may simultaneously trigger a life-threatening reaction. Anaesthetists should remain alert to the use of potentially allergenic agents employed by surgeons.
我们描述了一例 25 岁女性患者,因腰椎减压和微创手术而就诊,在手术接近尾声时出现过敏反应的临床症状。皮肤测试后来证实对左布比卡因和 MediShield(一种用于微创手术后的防粘连凝胶)过敏。这是首例确认的左布比卡因过敏反应病例。它还强调了多种药物可能同时引发危及生命的反应的可能性。麻醉师应始终警惕外科医生使用潜在的变应原药物。