2,6-二氨基蒽醌双脒对大鼠和仓鼠溶组织内阿米巴感染的影响。
The effect of bisamidines of 2,6-diaminoanthraquinone on Entamoeba histolytica infections in rats and hamsters.
作者信息
Burden E J, Carvajal S G, Fabio P F, Fields T L, Lin Y I, Murdock K C, Lang S A
出版信息
Experientia. 1979 Jan 15;35(1):33-5. doi: 10.1007/BF01917859.
PMID:217714
Abstract
Bisamidines of 2,6-diaminoanthraquinone have demonstrated potent activity against cecal and hepatic Entamoeba histolytica infections in rats and hamsters, respectively. A number of these compounds compared favorably, in overall drug efficacy, with metronidazole and other standard agents.
摘要
2,6-二氨基蒽醌双脒已分别在大鼠和仓鼠体内对盲肠和肝脏溶组织内阿米巴感染显示出强效活性。在总体药物疗效方面，这些化合物中的许多与甲硝唑及其他标准药物相比具有优势。
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本文引用的文献
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Induction of lung tumors and malignant lymphomas in mice by metronidazole.甲硝唑诱导小鼠肺部肿瘤和恶性淋巴瘤
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Carcinogens are mutagens: a simple test system combining liver homogenates for activation and bacteria for detection.致癌物是诱变剂：一种将用于活化的肝脏匀浆和用于检测的细菌相结合的简单测试系统。
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