Uncovering the role of invariant chain in controlling MHC class II antigen capture.
作者信息
Germain Ronald N
机构信息
Laboratory of Systems Biology, Lymphocyte Biology Section, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA.
出版信息
J Immunol. 2011 Aug 1;187(3):1073-5. doi: 10.4049/jimmunol.1101663.
Abstract
摘要
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本文引用的文献
1
Studies on hypersensitivity. II. Delayed hypersensitivity to denatured proteins in guinea pigs.超敏反应研究。II. 豚鼠对变性蛋白的迟发型超敏反应。
Immunology. 1959 Jan;2(1):64-70.
2
Large protein fragments as substrates for endocytic antigen capture by MHC class II molecules.作为MHC II类分子内吞抗原捕获底物的大蛋白质片段。
J Immunol. 1998 Oct 15;161(8):4048-57.
3
Cellular immune recognition and the biological role of major transplantation antigens.细胞免疫识别与主要移植抗原的生物学作用。
Biosci Rep. 1997 Apr;17(2):91-111. doi: 10.1023/a:1027303227595.
4
5
The MHC class II-associated invariant chain contains two endosomal targeting signals within its cytoplasmic tail.与MHC II类相关的恒定链在其胞质尾部含有两个内体靶向信号。
J Cell Sci. 1993 Nov;106 ( Pt 3):831-46. doi: 10.1242/jcs.106.3.831.
6
The invariant chain is required for intracellular transport and function of major histocompatibility complex class II molecules.恒定链是主要组织相容性复合体II类分子细胞内运输和功能所必需的。
J Exp Med. 1994 Feb 1;179(2):681-94. doi: 10.1084/jem.179.2.681.
7
MHC-dependent antigen processing and peptide presentation: providing ligands for T lymphocyte activation.主要组织相容性复合体（MHC）依赖性抗原加工与肽呈递：为T淋巴细胞激活提供配体
Cell. 1994 Jan 28;76(2):287-99. doi: 10.1016/0092-8674(94)90336-0.
8
Defective major histocompatibility complex class II assembly, transport, peptide acquisition, and CD4+ T cell selection in mice lacking invariant chain expression.缺乏恒定链表达的小鼠中主要组织相容性复合体II类组装、运输、肽获取及CD4+ T细胞选择存在缺陷。
J Exp Med. 1993 Jun 1;177(6):1699-712. doi: 10.1084/jem.177.6.1699.
9
The CLIP region of invariant chain plays a critical role in regulating major histocompatibility complex class II folding, transport, and peptide occupancy.恒定链的CLIP区域在调节主要组织相容性复合体II类分子的折叠、转运和肽占据方面发挥着关键作用。
J Exp Med. 1994 Sep 1;180(3):1107-13. doi: 10.1084/jem.180.3.1107.
10
Assembly, transport, and function of MHC class II molecules.MHC II类分子的组装、运输及功能
Annu Rev Immunol. 1994;12:259-93. doi: 10.1146/annurev.iy.12.040194.001355.
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