细胞免疫识别与主要移植抗原的生物学作用。
Cellular immune recognition and the biological role of major transplantation antigens.
作者信息
Zinkernagel R M
机构信息
Institute of Experimental Immunology, University of Zurich, Switzerland.
出版信息
Biosci Rep. 1997 Apr;17(2):91-111. doi: 10.1023/a:1027303227595.
PMID:9217962
Abstract
The experiments leading to the discovery of MHC-restricted T-cell killing of virus-infected cells are described. The implications of MHC- and HLA-restricted T-cell killing for the development of new vaccines and for the understanding of autoimmune disease are discussed.
摘要
描述了导致发现MHC限制的T细胞对病毒感染细胞杀伤作用的实验。讨论了MHC和HLA限制的T细胞杀伤作用对新型疫苗开发以及对自身免疫性疾病理解的影响。
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