Department of Human Nutrition, Faculty of Life Sciences, University of Copenhagen, 1958 Frederiksberg C, Denmark.
Pediatr Res. 2011 Nov;70(5):501-6. doi: 10.1203/PDR.0b013e31822d7470.
LBW increases the risk of a number of noncommunicable diseases in adulthood. However, birth weight (BW) cannot describe variability in infant body composition (BC). Variability in fat mass (FM) and fat-free mass (FFM) at birth may be particularly important in low-income countries because they undergo nutritional transition. There is a need for data on birth BC and its predictors from low-income countries in transition. We assessed absolute FM and FFM at birth and examined the role of gender, parity, GA, and LBW as predictors of birth BC. FM and FFM were assessed within 48 h of birth on 350 Ethiopian newborns using air displacement plethysmography (ADP). Female gender and being an infant of primi- or secundiparous mothers predicted lower BW and lower birth FFM but not FM, compared with male gender and infants of multiparous mothers, respectively. There was a positive linear relationship between BW and relative amount of FM for boys and girls. This study presents reference data on birth FM and FFM from a low-income setting and provides background for further longitudinal mapping of the relationship between fetal BC, childhood growth, and adult disease.
LBW 会增加成年后患多种非传染性疾病的风险。然而，出生体重（BW）并不能描述婴儿身体成分（BC）的变异性。出生时脂肪量（FM）和去脂体重（FFM）的变异性在低收入国家可能尤为重要，因为这些国家正在经历营养转型。需要来自转型期低收入国家的关于出生 BC 及其预测因素的数据。我们评估了 350 名埃塞俄比亚新生儿出生时的绝对 FM 和 FFM，并研究了性别、产次、GA 和 LBW 作为出生 BC 预测因素的作用。使用空气置换体积描记法（ADP）在出生后 48 小时内评估 FM 和 FFM。与多产母亲的婴儿相比，女性性别和初产妇或经产妇的婴儿分别预测 BW 较低和出生时 FFM 较低，但不预测 FM 较低。男孩和女孩的 BW 与 FM 的相对量之间存在正线性关系。本研究提供了来自低收入环境的出生时 FM 和 FFM 的参考数据，并为进一步纵向研究胎儿 BC、儿童生长和成年疾病之间的关系提供了背景。
