Neurology/Neurosurgery Intensive Care Unit, Washington University, St. Louis, MO, USA.
Neurocrit Care. 2011 Sep;15(2):211-40. doi: 10.1007/s12028-011-9605-9.
Subarachnoid hemorrhage (SAH) is an acute cerebrovascular event which can have devastating effects on the central nervous system as well as a profound impact on several other organs. SAH patients are routinely admitted to an intensive care unit and are cared for by a multidisciplinary team. A lack of high quality data has led to numerous approaches to management and limited guidance on choosing among them. Existing guidelines emphasize risk factors, prevention, natural history, and prevention of rebleeding, but provide limited discussion of the complex critical care issues involved in the care of SAH patients. The Neurocritical Care Society organized an international, multidisciplinary consensus conference on the critical care management of SAH to address this need. Experts from neurocritical care, neurosurgery, neurology, interventional neuroradiology, and neuroanesthesiology from Europe and North America were recruited based on their publications and expertise. A jury of four experienced neurointensivists was selected for their experience in clinical investigations and development of practice guidelines. Recommendations were developed based on literature review using the GRADE system, discussion integrating the literature with the collective experience of the participants and critical review by an impartial jury. Recommendations were developed using the GRADE system. Emphasis was placed on the principle that recommendations should be based not only on the quality of the data but also tradeoffs and translation into practice. Strong consideration was given to providing guidance and recommendations for all issues faced in the daily management of SAH patients, even in the absence of high quality data.
蛛网膜下腔出血 (SAH) 是一种急性脑血管事件,可对中枢神经系统造成严重影响,并对其他多个器官产生深远影响。SAH 患者通常被收入重症监护病房,并由多学科团队进行护理。由于缺乏高质量的数据,导致出现了许多管理方法,但对于如何选择这些方法,只有有限的指导。现有的指南强调了危险因素、预防、自然史和再出血的预防,但对涉及 SAH 患者护理的复杂重症监护问题讨论有限。神经重症监护学会组织了一次关于 SAH 重症监护管理的国际、多学科共识会议,以满足这一需求。根据他们的出版物和专业知识,从神经重症监护、神经外科、神经病学、介入神经放射学和神经麻醉学领域招募了来自欧洲和北美的专家。四名经验丰富的神经重症监护专家因在临床研究和实践指南制定方面的经验而被选为评审团成员。建议是根据 GRADE 系统的文献回顾、结合参与者的集体经验进行讨论以及由公正的评审团进行批判性审查而制定的。建议是使用 GRADE 系统制定的。重点是建议不仅应基于数据的质量,还应基于权衡和转化为实践。即使在缺乏高质量数据的情况下,也非常重视为 SAH 患者日常管理中面临的所有问题提供指导和建议。