Jin K M, Nogita T, Toyoda H, Kawashima M, Hidano A
Department of Dermatology, Tokyo Women's Medical College, Japan.
J Dermatol. 1990 Sep;17(9):555-8. doi: 10.1111/j.1346-8138.1990.tb01694.x.
We describe a 52-year-old man with a pedunculated pigmented eccrine poroma mimicking a nodular malignant melanoma in the occipital region. The tumor was once resected but soon recurred. Histologically, the tumor mass extended from the epidermis downwards into the dermis and contained melanin granules in some areas. The tumor cells were uniformly cuboidal in appearance and had round, deeply basophilic nuclei. Initially, the urinary excretion level of 5-S-cysteinyldopa (5-S-CD) was high, but, after resection of the tumor, the level of 5-S-CD returned to normal.
我们描述了一名52岁男性,其枕部有一个带蒂的色素性小汗腺汗孔瘤,酷似结节性恶性黑色素瘤。该肿瘤曾被切除,但很快复发。组织学上,肿瘤块从表皮向下延伸至真皮,部分区域含有黑色素颗粒。肿瘤细胞外观均一呈立方形,有圆形、深嗜碱性核。最初,5-S-半胱氨酰多巴(5-S-CD)的尿排泄水平较高,但肿瘤切除后,5-S-CD水平恢复正常。