Defense of the Lungs Project, Pulmonary Disease/Critical Care, Department of Pediatrics, University of Minnesota Medical School, Minneapolis, MN 55455, USA.
IEEE Trans Biomed Eng. 2012 Jan;59(1):106-14. doi: 10.1109/TBME.2011.2161608. Epub 2011 Jul 18.
High-frequency chest compression (HFCC), using an appropriate source (pump) waveform for frequencies at or above 3 Hz, can enhance pulmonary clearance for patients with cystic fibrosis (CF) and chronic obstructive pulmonary disease (COPD). Using a trapezoidal HFCC source pressure waveform, secretion of water from epithelial tissue and transport of mucus through lung airways can be enhanced for patients with CF and COPD. At frequencies below 3 Hz, low-frequency chest compression (LFCC) appears to have a significant impact on the cardiovascular system. For a trapezoidal source pressure waveform at frequencies close to 1 Hz, LFCC produces amplitude or intensity variations in various components of the electrocardiogram time-domain waveform, produces changes at very low frequencies associated with the electrocardiogram frequency spectra (indicating enhanced parasympathetic nervous system activity), and promotes a form of heart rate synchronization. It appears that LFCC can also provide additional cardiovascular benefits by reducing peak and average systolic and diastolic blood pressure for patients with hypertension.
高频胸壁压缩（HFCC）使用适当的源（泵）波形，频率在 3 Hz 或以上，可以增强囊性纤维化（CF）和慢性阻塞性肺疾病（COPD）患者的肺部清除能力。使用梯形 HFCC 源压力波形，可以增强 CF 和 COPD 患者的上皮组织水分分泌和粘液通过肺气道的运输。在 3 Hz 以下的频率下，低频胸壁压缩（LFCC）似乎对心血管系统有重大影响。对于接近 1 Hz 的梯形源压力波形，LFCC 会在心电图时域波形的各个分量中产生幅度或强度变化，产生与心电图频谱相关的极低频率变化（表明增强的副交感神经系统活动），并促进一种心率同步形式。LFCC 似乎还可以通过降低高血压患者的收缩压和舒张压峰值和平均水平来提供额外的心血管益处。
