Vision Health Services, Ikeja, Lagos State, Nigeria.
Invest Ophthalmol Vis Sci. 2011 Aug 24;52(9):6714-9. doi: 10.1167/iovs.11-7293.
To estimate prevalence and describe causes of functional low vision (FLV) among a nationally representative sample of Nigerian adults, assess socioeconomic risk factors, and estimate the number of adults in Nigeria who might benefit from low vision assessment or rehabilitation services.
Multistage, stratified, cluster random sampling with probability proportional to size procedures were used to identify a nationally representative sample of 15,027 persons aged 40 years or older. Distance vision was measured using a reduced logMAR tumbling E-chart. All participants with presenting acuity of <6/12 in one or both eyes had their corrected acuity measured and underwent detailed clinical examination to determine the cause. FLV was defined as best corrected vision <6/18 in the better eye, after excluding those with no light perception in both eyes and those with treatable causes. Analysis took account of the clustered design.
In all, 13,591 individuals were examined in 305 clusters (response rate, 89.9%). The crude prevalence of FLV was 3.5% (95% confidence interval, 3.1-3.9%). This was lower than the prevalence of blindness, which was 4.2%. Glaucoma was the most common cause and age the most important risk factor. There are estimated to be approximately 5000 adults with FLV per million population and 340 who are totally blind. Only 9.3% of those with FLV were of working age and literate.
These are the first data on the prevalence, causes, and risk factors for FLV from Africa. Results support studies from Asia that the prevalence of FLV is lower than previously thought. Because the majority of adults with FLV in Nigeria live in rural areas and are elderly and not literate, further research is required to assess the nature of the interventions required and who might best deliver them.
估计尼日利亚成年人中功能型低视力(FLV)的流行率和病因,并评估社会经济风险因素,估计尼日利亚有多少成年人可能受益于低视力评估或康复服务。
采用多阶段、分层、集群随机抽样方法,按大小比例概率进行抽样,确定了一个具有全国代表性的 15027 名 40 岁及以上成年人样本。使用简化对数 MAR 滚动 E 图表测量远距离视力。所有一眼或两眼视力在 6/12 以下的参与者都进行了矫正视力测量,并进行了详细的临床检查以确定病因。FLV 定义为矫正后较好眼视力 <6/18,但排除两眼无光感和可治疗病因者。分析考虑了集群设计。
共有 305 个集群(应答率为 89.9%)的 13591 人接受了检查。FLV 的粗患病率为 3.5%(95%置信区间为 3.1-3.9%)。这低于失明的患病率(4.2%)。青光眼是最常见的病因,年龄是最重要的危险因素。估计每百万人口中有 5000 名成年人患有 FLV,有 340 人完全失明。只有 9.3%的 FLV 患者处于工作年龄且识字。
这是非洲首次关于 FLV 的流行率、病因和危险因素的数据。结果支持亚洲的研究,表明 FLV 的流行率低于之前的预期。由于尼日利亚大多数 FLV 患者居住在农村地区,年龄较大且不识字,因此需要进一步研究以评估所需干预措施的性质以及谁最适合提供这些干预措施。