Scripps Whittier Diabetes Institute, La Jolla, CA, USA.
Diabetes Care. 2011 Sep;34(9):1926-31. doi: 10.2337/dc10-2081. Epub 2011 Jul 20.
To evaluate the effect of a culturally sensitive diabetes self-management education program that uses a low-cost, peer-educator format (Project Dulce) on glucose control and metabolic parameters in low-income Mexican Americans with type 2 diabetes.
A total of 207 Mexican-American patients recruited from federally funded community health centers in San Diego County with HbA(1c) >8% were randomly assigned to the Project Dulce peer intervention or continuation of standard diabetes care. The primary outcome of interest was HbA(1c).
The majority of subjects were born in Mexico, were female, were middle-aged, had less than an eighth-grade education, and had high baseline HbA(1c) levels. Significant time-by-group interaction effects for HbA(1c) (P = 0.02) and diastolic blood pressure (P = 0.04) indicated that the Project Dulce group exhibited greater improvement (i.e., decreases) across time. Within-group analyses showed that the intervention group exhibited significant improvements from baseline to month 4 in absolute levels of HbA(1c) (-1.7%, P = 0.001) and HDL cholesterol (+1.4 mg/dL, P = 0.01) and from baseline to month 10 in absolute levels of HbA(1c) (-1.5%, P = 0.01), total cholesterol (-7.2 mg/dL, P = 0.04), HDL cholesterol (+1.6 mg/dL, P = 0.01), and LDL cholesterol (-8.1 mg/dL, P = 0.02). No significant changes were noted in the control group.
This randomized trial, using the Project Dulce model of culturally sensitive, peer-led education, demonstrates improvement in glucose and metabolic control and suggests that this low-cost approach to self-management education for high-risk diabetic populations is effective.
评估一种使用低成本、同伴教育者形式( Dulce 项目)的文化敏感型糖尿病自我管理教育计划对 2 型糖尿病的低收入墨西哥裔美国人的血糖控制和代谢参数的影响。
从圣地亚哥县联邦资助的社区健康中心招募了 207 名 HbA(1c)>8%的墨西哥裔美国患者,随机分配到 Dulce 项目同伴干预组或继续接受标准糖尿病护理。主要观察指标为 HbA(1c)。
大多数受试者出生在墨西哥,女性,年龄中等,受教育程度不到八年级,基线 HbA(1c)水平较高。HbA(1c)(P=0.02)和舒张压(P=0.04)的显著时间-组交互效应表明 Dulce 项目组在整个时间内表现出更大的改善(即降低)。组内分析显示,干预组在 HbA(1c)绝对值(-1.7%,P=0.001)和 HDL 胆固醇(+1.4mg/dL,P=0.01)方面从基线到第 4 个月显著改善,在 HbA(1c)绝对值(-1.5%,P=0.01)、总胆固醇(-7.2mg/dL,P=0.04)、HDL 胆固醇(+1.6mg/dL,P=0.01)和 LDL 胆固醇(-8.1mg/dL,P=0.02)方面从基线到第 10 个月显著改善。对照组无显著变化。
这项随机试验采用 Dulce 模型进行文化敏感、同伴主导的教育,显示出对血糖和代谢控制的改善,并表明这种针对高危糖尿病人群的低成本自我管理教育方法是有效的。