Department of Chemistry and the Molecular Design Institute, New York University, 100 Washington Square East, New York, NY 10003-6688, USA.
Science. 2011 Jul 22;333(6041):436-40. doi: 10.1126/science.1204369.
Self-assembly of multiple components into well-defined and predictable structures remains one of the foremost challenges in chemistry. Here, we report on the rational design of a supramolecular cage assembled from 20 ions of three distinct species through 72 hydrogen bonds. The cage is constructed from two kinds of hexagonal molecular tiles, a tris(guanidinium)nitrate cluster and a hexa(4-sulfonatophenyl)benzene, joined at their edges through complementary and metrically matched N-H···O-S hydrogen bonds to form a truncated octahedron, one of the Archimedean polyhedra. The truncated octahedron, with an interior volume of 2200 cubic angstroms, serves as the composite building unit of a body-centered cubic zeolite-like framework, which exhibits an ability to encapsulate a wide range of differently charged species, including organic molecules, transition metal complexes, and "ship-in-a-bottle" nanoclusters not observed otherwise.
自组装多个组件成明确和可预测的结构仍然是化学中的最前沿的挑战之一。在这里，我们报告了一个超分子笼的合理设计，它是由三种不同物种的 20 个离子通过 72 个氢键组装而成的。该笼由两种六边形分子瓦片组成，一种是三（胍）硝酸盐簇，另一种是六（4-磺酸钠基）苯，通过互补和计量匹配的 N-H···O-S 氢键连接在它们的边缘，形成一个截角八面体，这是阿基米德多面体之一。该截角八面体的内部体积为 2200 立方埃，作为体心立方沸石样骨架的复合构建单元，它表现出包裹各种不同电荷物种的能力，包括有机分子、过渡金属配合物和“船在瓶中”纳米簇，这些在其他情况下是观察不到的。
