Hirose Takahisa, Hasegawa Jun, Izawa Sachiko, Enoki Hiromi, Kuzuya Masafumi
Department of Geriatric Medicine, Nagoya Medical University.
Nihon Ronen Igakkai Zasshi. 2011;48(2):163-9. doi: 10.3143/geriatrics.48.163.
In our aging society, the number of community-dwelling dependent elderly people is increasing. Many studies have shown that depression influences the health of older persons. In the present study, we examined whether depressive status is associated with mortality and hospitalization in community-dwelling dependent older people during a 3-year follow-up period.
This study was a prospective cohort analysis of 1,409 community-dwelling disabled elderly (489 men, 920 women; average age 80.1, the Nagoya Longitudinal Study for Frail Elderly). Data included demographic characteristics, basic activities of daily living (ADL) scores, comorbidity, and depressive status as assessed by the short version of the Geriatric Depression Scale (GDS-15) at baseline. The participants were considered to have depression or severe depression if their GDS-15 score was 6-10 or above 10, respectively. The Cox proportional hazard model and the Kaplan-Meier method were used to assess any association with depressive status at baseline with mortality or hospitalization during a 3-year period.
During a 3-year observation, 284 participants died (53 at home, 231 at hospital), and 576 were admitted to hospitals. Univariate analysis revealed that the depressive status of participants was associated with mortality and hospitalization during a 3-year follow up. However, multivariate models used to adjust for potential confounders including gender, age, ADL status, and comorbidity, did not show any association between depressive status and mortality and hospitalization.
Depressive status among community-dwelling disabled elderly was not associated with mortality or hospitalization in the present series.
在我们这个老龄化社会中，居住在社区的依赖他人照料的老年人数量正在增加。许多研究表明，抑郁症会影响老年人的健康。在本研究中，我们调查了在为期3年的随访期内，居住在社区的依赖他人照料的老年人的抑郁状态是否与死亡率和住院率相关。
本研究是对1409名居住在社区的残疾老年人（489名男性，920名女性；平均年龄80.1岁，名古屋虚弱老年人纵向研究）进行的前瞻性队列分析。数据包括人口统计学特征、日常生活活动（ADL）评分、合并症，以及基线时通过老年抑郁量表简版（GDS-15）评估的抑郁状态。如果参与者的GDS-15评分分别为6-10或高于10，则被认为患有抑郁症或重度抑郁症。采用Cox比例风险模型和Kaplan-Meier方法评估基线时的抑郁状态与3年内死亡率或住院率之间的任何关联。
在3年的观察期内，284名参与者死亡（53人在家中死亡，231人在医院死亡），576人住院。单因素分析显示，参与者的抑郁状态与3年随访期间的死亡率和住院率相关。然而，用于调整包括性别、年龄、ADL状态和合并症等潜在混杂因素的多变量模型并未显示抑郁状态与死亡率和住院率之间存在任何关联。
在本系列研究中，居住在社区的残疾老年人的抑郁状态与死亡率或住院率无关。
