Department of Public Health & Primary Care, Institute of Public Health, Cambridge University, UK; NIHR Collaboration for Leadership in Applied Health Research & Care for Cambridgeshire & Peterborough (CLAHRC-CP), UK; King's College London, Institute of Psychiatry, Health Service and Population Research Department, Centre for Global Mental Health, London, UK.
Department of Public Health & Primary Care, Institute of Public Health, Cambridge University, UK.
J Psychosom Res. 2015 Jan;78(1):25-33. doi: 10.1016/j.jpsychores.2014.11.002. Epub 2014 Nov 8.
This paper aims to systematically review observational studies that have analysed whether depressive symptoms in the community are associated with higher general hospital admissions, longer hospital stays and increased risk of re-admission.
We identified prospective studies that looked at depressive symptoms in the community as a risk factor for non-psychiatric general hospital admissions, length of stay or risk of re-admission. The search was carried out on MEDLINE, PsycINFO, Cochrane Library Database, and followed up with contact with authors and scanning of reference lists.
Eleven studies fulfilled our inclusion and exclusion criteria, and all were deemed to be of moderate to high quality. Meta-analysis of seven studies with relevant data suggested that depressive symptoms may be a predictor of subsequent admission to a general hospital in unadjusted analyses (RR=1.36, 95% CI: 1.28-1.44), but findings after adjustment for confounding variables were inconsistent. The narrative synthesis also reported depressive symptoms to be independently associated with longer length of stay, and higher re-admission risk.
Depressive symptoms are associated with a higher risk of hospitalisation, longer length of stay and a higher re-admission risk. Some of these associations may be mediated by other factors, and should be explored in more details.
本文旨在系统回顾观察性研究，分析社区中的抑郁症状是否与更高的综合医院入院率、更长的住院时间和更高的再入院风险相关。
我们确定了前瞻性研究，这些研究将社区中的抑郁症状视为非精神科综合医院入院、住院时间或再入院风险的危险因素。搜索在 MEDLINE、PsycINFO、Cochrane 图书馆数据库进行，并通过与作者联系和扫描参考文献进行了跟进。
符合纳入和排除标准的研究有 11 项，且均被认为具有中等到高度的质量。对 7 项具有相关数据的研究进行荟萃分析表明，在未调整的分析中，抑郁症状可能是随后综合医院入院的预测因素（RR=1.36，95%CI：1.28-1.44），但调整混杂变量后的结果不一致。叙述性综合报告还指出，抑郁症状与更长的住院时间和更高的再入院风险独立相关。
抑郁症状与更高的住院风险、更长的住院时间和更高的再入院风险相关。其中一些关联可能由其他因素介导，应进一步详细探讨。
