Ragsdale Mary I, Lehmer Larisa M, Ragsdale Bruce D, Chow Warren A, Carson Robert T
New York Medical College, Valhalla, USA.
Am J Dermatopathol. 2011 Aug;33(6):e70-3. doi: 10.1097/DAD.0b013e318214a7ea.
As a primary malignant bone tumor, osteosarcoma is second only to chondrosarcoma. Although it commonly metastasizes and is aggressive in nature, it rarely colonizes the skin. This is a report of a 22-year-old male with osteosarcoma of the pelvis and metastasis to the lungs and chest wall who developed a clinically unsuspected solitary cutaneous metastasis in the scalp. Instead of the expected cyst, incisional biopsy disclosed a solid tan nodule of chondro-osseous sarcoma. Although rare, cutaneous metastases from osteosarcoma may appear in skin, especially the scalp, or in skin over the primary tumor. New skin lesions in a patient with a history of osteosarcoma warrant investigations including imaging and biopsy.
骨肉瘤作为一种原发性恶性骨肿瘤,仅次于软骨肉瘤。尽管它通常会发生转移且具有侵袭性,但很少转移至皮肤。本文报告了一名22岁男性,患有骨盆骨肉瘤并已转移至肺部和胸壁,却在头皮出现了临床未怀疑的孤立性皮肤转移灶。切开活检显示,病变并非预期的囊肿,而是一个实性黄褐色的软骨骨肉瘤结节。骨肉瘤的皮肤转移虽罕见,但可能出现在皮肤,尤其是头皮,或原发性肿瘤上方的皮肤。有骨肉瘤病史的患者出现新的皮肤病变时,需要进行包括影像学检查和活检在内的相关检查。