一例疑似科萨科夫综合征：一种额叶和间脑结构发病机制的综合征，并与内侧颞叶痴呆相比较
A case of probable korsakoff's syndrome: a syndrome of frontal lobe and diencephalic structural pathogenesis and a comparison with medial temporal lobe dementias.
作者信息
Spiegel David R, Lim Kheng-Jim
机构信息
Department of Psychiatry and Behavioral Sciences, Eastern Virginia Medical School, Norfolk, Virginia, USA.
出版信息
Innov Clin Neurosci. 2011 Jun;8(6):15-9.
Abstract
Korsakoff's Syndrome is an amnestic disorder that involves both anterograde and retrograde amnesia. Traditionally associated with longstanding alcohol misuse, thiamine deficiency has been long posited in its pathogenesis, as has dienecephalic lesions. Yet, through this case report, we highlight similarities (and differences) with medial temporal lobe memory disorders and the role of frontal lobe dysfunction in its retrograde amnesia.
摘要
科萨科夫综合征是一种涉及顺行性和逆行性失忆的遗忘症。传统上与长期滥用酒精有关，硫胺素缺乏长期以来一直被认为在其发病机制中起作用，间脑病变也是如此。然而，通过本病例报告，我们强调了它与内侧颞叶记忆障碍的异同，以及额叶功能障碍在其逆行性失忆中的作用。
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2
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Alcohol Alcohol. 2009 Mar-Apr;44(2):148-54. doi: 10.1093/alcalc/agn118. Epub 2009 Jan 16.
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Alcohol Alcohol. 2008 Jan-Feb;43(1):70-2. doi: 10.1093/alcalc/agm158. Epub 2007 Nov 5.
4
Frontal-subcortical circuitry and behavior.额叶-皮质下神经回路与行为
Dialogues Clin Neurosci. 2007;9(2):141-51. doi: 10.31887/DCNS.2007.9.2/rbonelli.
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Learn Mem. 2006 Nov-Dec;13(6):699-710. doi: 10.1101/lm.357406. Epub 2006 Nov 13.
6
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