Instituto Universitario de Química Organometálica Enrique Moles, Unidad Asociada al CSIC, Universidad de Oviedo, Julián Clavería 8, 33006, Oviedo, Spain.
Org Biomol Chem. 2011 Oct 7;9(19):6469-80. doi: 10.1039/c1ob05750b. Epub 2011 Jul 21.
Indoles are the most abundant heterocycles in biologically active natural products, pharmaceuticals, agrochemicals, and are relevant substructures in functional materials. As a result, the development of methodologies that enable the synthesis of these compounds is continuously demanded. This review summarizes most recent and relevant approaches towards the preparation of this prevalent structural motif.
吲哚是生物活性天然产物、药物、农用化学品中最丰富的杂环,也是功能材料中相关的亚结构。因此,不断需要开发能够合成这些化合物的方法学。本文综述了最近关于制备这种常见结构基序的相关方法。